The Carbamate Kinase-Like Carbamoyl Phosphate Synthetase of the Hyperthermophilic Archaeon Pyrococcus furiosus, a Missing Link in the Evolution of Carbamoyl Phosphate Biosynthesis

Microbial carbamoyl phosphate synthetases (CPS) use glutamine as nitrogen donor and are composed of two subunits (or domains), one exhibiting glutaminase activity, the other able to synthesize carbamoyl phosphate (CP) from bicarbonate, ATP, and ammonia. The pseudodimeric organization of this synthet...

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 1997-11, Vol.94 (24), p.12803-12808
Hauptverfasser: Durbecq, Virginie, Legrain, Christianne, Roovers, Martine, Piérard, André, Glansdorff, Nicolas
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Sprache:eng
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