Suspected invasive placenta: evaluation with magnetic resonance imaging
Purpose To determine the utility of magnetic resonance imaging (MRI) in diagnosing invasive placenta (IP). Materials and methods MRI findings in 32 women with suspected IP were evaluated independently by four readers. Interobserver agreement was calculated with kappa (κ) statistics. Associations bet...
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| Veröffentlicht in: | European radiology 2014-12, Vol.24 (12), p.3150-3160 |
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| creator | Bour, Laurence Placé, Vinciane Bendavid, Sandra Fargeaudou, Yann Portal, Jean-Jacques Ricbourg, Aude Sebbag, Delphine Dohan, Anthony Vicaut, Eric Soyer, Philippe |
| description | Purpose
To determine the utility of magnetic resonance imaging (MRI) in diagnosing invasive placenta (IP).
Materials and methods
MRI findings in 32 women with suspected IP were evaluated independently by four readers. Interobserver agreement was calculated with kappa (κ) statistics. Associations between MRI findings and IP were assessed by univariate and multivariate analyses. Sensitivity, specificity and accuracy of MRI for the diagnosis of IP were estimated.
Results
Sixteen women (16/32; 50 %) had confirmed IP. Interobserver correlation for the diagnosis of IP was fair (κ = 0.40). Univariate analysis revealed that thinning or focal defect of the uteroplacental interface (
P
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| doi_str_mv | 10.1007/s00330-014-3354-z |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1625349406</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3494532551</sourcerecordid><originalsourceid>FETCH-LOGICAL-c442t-a9de2c4bf846916dc27ea0c3e671f681c3f844a58821c239869d9a82101f94573</originalsourceid><addsrcrecordid>eNp1kM9LwzAUx4Mobk7_AC9S8OKl-vKjTeNNhk5h4EE9hyx9nR1dWpt24v56M6oigqfw8j7vm7wPIacULimAvPIAnEMMVMScJyLe7pExFZzFFDKxT8ageBZLpcSIHHm_AgBFhTwkI5aABCbFmMyeet-g7TCPSrcxvtxg1FTGouvMdYQbU_WmK2sXvZfda7Q2S4ddaaMWfe2MsxiV4a50y2NyUJjK48nXOSEvd7fP0_t4_jh7mN7MYysE62KjcmRWLIpMpIqmuWUSDViOqaRFmlHLQ0eYJMsYtYyrLFW5MqEAWiiRSD4hF0Nu09ZvPfpOr0tvsaqMw7r3mqYs4UIJSAN6_gdd1X3rwu92lMgkA8oDRQfKtrX3LRa6acNO7YemoHeW9WBZB8t6Z1lvw8zZV3K_WGP-M_GtNQBsAHxouSW2v57-N_UTsd2G0Q</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1624872013</pqid></control><display><type>article</type><title>Suspected invasive placenta: evaluation with magnetic resonance imaging</title><source>MEDLINE</source><source>SpringerLink Journals - AutoHoldings</source><creator>Bour, Laurence ; Placé, Vinciane ; Bendavid, Sandra ; Fargeaudou, Yann ; Portal, Jean-Jacques ; Ricbourg, Aude ; Sebbag, Delphine ; Dohan, Anthony ; Vicaut, Eric ; Soyer, Philippe</creator><creatorcontrib>Bour, Laurence ; Placé, Vinciane ; Bendavid, Sandra ; Fargeaudou, Yann ; Portal, Jean-Jacques ; Ricbourg, Aude ; Sebbag, Delphine ; Dohan, Anthony ; Vicaut, Eric ; Soyer, Philippe</creatorcontrib><description>Purpose
To determine the utility of magnetic resonance imaging (MRI) in diagnosing invasive placenta (IP).
Materials and methods
MRI findings in 32 women with suspected IP were evaluated independently by four readers. Interobserver agreement was calculated with kappa (κ) statistics. Associations between MRI findings and IP were assessed by univariate and multivariate analyses. Sensitivity, specificity and accuracy of MRI for the diagnosis of IP were estimated.
Results
Sixteen women (16/32; 50 %) had confirmed IP. Interobserver correlation for the diagnosis of IP was fair (κ = 0.40). Univariate analysis revealed that thinning or focal defect of the uteroplacental interface (
P
< 0.0001) was the most discriminating MRI variable in the differentiation between normal and IP. Overall sensitivity and specificity of MRI for the diagnosis of IP were 84 % [95 % CI: 75–94 %] and 80 % [95 % CI: 66–93 %], respectively. Thinning or focal defect of the uteroplacental interface was the most accurate finding (88 %) in the diagnosis of IP. Multivariate analysis revealed that thinning or focal defect of the uteroplacental interface was the single independent predictor of IP (
P
= 0.0006; OR = 64.99).
Conclusion
MR imaging has 84 % sensitivity [95 % CI: 75–94 %] and 80 % specificity [95 % CI: 66–93 %] for the diagnosis of IP. Thinning or focal defect of the uteroplacental interface is the most discriminating independent MR variable in differentiating between normal placenta and IP.
Key points
• MR imaging has acceptable degrees of accuracy to diagnose invasive placenta.
• Focal uteroplacental interface defect is the best finding to diagnose invasive placenta.
• Focal uteroplacental interface defect is the single independent predictor of invasive placenta.</description><identifier>ISSN: 0938-7994</identifier><identifier>EISSN: 1432-1084</identifier><identifier>DOI: 10.1007/s00330-014-3354-z</identifier><identifier>PMID: 25070274</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Adult ; Cesarean section ; Diagnosis, Differential ; Diagnostic Radiology ; Female ; Humans ; Imaging ; Internal Medicine ; Interventional Radiology ; Magnetic resonance imaging ; Magnetic Resonance Imaging - methods ; Medicine ; Medicine & Public Health ; Neuroradiology ; Observer Variation ; Placenta ; Placenta - pathology ; Placenta Accreta - diagnosis ; Placenta Previa - diagnosis ; Pregnancy ; Pregnancy complications ; Radiology ; Sensitivity and Specificity ; Ultrasonic imaging ; Ultrasound ; Urogenital ; Young Adult</subject><ispartof>European radiology, 2014-12, Vol.24 (12), p.3150-3160</ispartof><rights>European Society of Radiology 2014</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c442t-a9de2c4bf846916dc27ea0c3e671f681c3f844a58821c239869d9a82101f94573</citedby><cites>FETCH-LOGICAL-c442t-a9de2c4bf846916dc27ea0c3e671f681c3f844a58821c239869d9a82101f94573</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00330-014-3354-z$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00330-014-3354-z$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,777,781,27905,27906,41469,42538,51300</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25070274$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bour, Laurence</creatorcontrib><creatorcontrib>Placé, Vinciane</creatorcontrib><creatorcontrib>Bendavid, Sandra</creatorcontrib><creatorcontrib>Fargeaudou, Yann</creatorcontrib><creatorcontrib>Portal, Jean-Jacques</creatorcontrib><creatorcontrib>Ricbourg, Aude</creatorcontrib><creatorcontrib>Sebbag, Delphine</creatorcontrib><creatorcontrib>Dohan, Anthony</creatorcontrib><creatorcontrib>Vicaut, Eric</creatorcontrib><creatorcontrib>Soyer, Philippe</creatorcontrib><title>Suspected invasive placenta: evaluation with magnetic resonance imaging</title><title>European radiology</title><addtitle>Eur Radiol</addtitle><addtitle>Eur Radiol</addtitle><description>Purpose
To determine the utility of magnetic resonance imaging (MRI) in diagnosing invasive placenta (IP).
Materials and methods
MRI findings in 32 women with suspected IP were evaluated independently by four readers. Interobserver agreement was calculated with kappa (κ) statistics. Associations between MRI findings and IP were assessed by univariate and multivariate analyses. Sensitivity, specificity and accuracy of MRI for the diagnosis of IP were estimated.
Results
Sixteen women (16/32; 50 %) had confirmed IP. Interobserver correlation for the diagnosis of IP was fair (κ = 0.40). Univariate analysis revealed that thinning or focal defect of the uteroplacental interface (
P
< 0.0001) was the most discriminating MRI variable in the differentiation between normal and IP. Overall sensitivity and specificity of MRI for the diagnosis of IP were 84 % [95 % CI: 75–94 %] and 80 % [95 % CI: 66–93 %], respectively. Thinning or focal defect of the uteroplacental interface was the most accurate finding (88 %) in the diagnosis of IP. Multivariate analysis revealed that thinning or focal defect of the uteroplacental interface was the single independent predictor of IP (
P
= 0.0006; OR = 64.99).
Conclusion
MR imaging has 84 % sensitivity [95 % CI: 75–94 %] and 80 % specificity [95 % CI: 66–93 %] for the diagnosis of IP. Thinning or focal defect of the uteroplacental interface is the most discriminating independent MR variable in differentiating between normal placenta and IP.
Key points
• MR imaging has acceptable degrees of accuracy to diagnose invasive placenta.
• Focal uteroplacental interface defect is the best finding to diagnose invasive placenta.
• Focal uteroplacental interface defect is the single independent predictor of invasive placenta.</description><subject>Adult</subject><subject>Cesarean section</subject><subject>Diagnosis, Differential</subject><subject>Diagnostic Radiology</subject><subject>Female</subject><subject>Humans</subject><subject>Imaging</subject><subject>Internal Medicine</subject><subject>Interventional Radiology</subject><subject>Magnetic resonance imaging</subject><subject>Magnetic Resonance Imaging - methods</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Neuroradiology</subject><subject>Observer Variation</subject><subject>Placenta</subject><subject>Placenta - pathology</subject><subject>Placenta Accreta - diagnosis</subject><subject>Placenta Previa - diagnosis</subject><subject>Pregnancy</subject><subject>Pregnancy complications</subject><subject>Radiology</subject><subject>Sensitivity and Specificity</subject><subject>Ultrasonic imaging</subject><subject>Ultrasound</subject><subject>Urogenital</subject><subject>Young Adult</subject><issn>0938-7994</issn><issn>1432-1084</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp1kM9LwzAUx4Mobk7_AC9S8OKl-vKjTeNNhk5h4EE9hyx9nR1dWpt24v56M6oigqfw8j7vm7wPIacULimAvPIAnEMMVMScJyLe7pExFZzFFDKxT8ageBZLpcSIHHm_AgBFhTwkI5aABCbFmMyeet-g7TCPSrcxvtxg1FTGouvMdYQbU_WmK2sXvZfda7Q2S4ddaaMWfe2MsxiV4a50y2NyUJjK48nXOSEvd7fP0_t4_jh7mN7MYysE62KjcmRWLIpMpIqmuWUSDViOqaRFmlHLQ0eYJMsYtYyrLFW5MqEAWiiRSD4hF0Nu09ZvPfpOr0tvsaqMw7r3mqYs4UIJSAN6_gdd1X3rwu92lMgkA8oDRQfKtrX3LRa6acNO7YemoHeW9WBZB8t6Z1lvw8zZV3K_WGP-M_GtNQBsAHxouSW2v57-N_UTsd2G0Q</recordid><startdate>20141201</startdate><enddate>20141201</enddate><creator>Bour, Laurence</creator><creator>Placé, Vinciane</creator><creator>Bendavid, Sandra</creator><creator>Fargeaudou, Yann</creator><creator>Portal, Jean-Jacques</creator><creator>Ricbourg, Aude</creator><creator>Sebbag, Delphine</creator><creator>Dohan, Anthony</creator><creator>Vicaut, Eric</creator><creator>Soyer, Philippe</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20141201</creationdate><title>Suspected invasive placenta: evaluation with magnetic resonance imaging</title><author>Bour, Laurence ; Placé, Vinciane ; Bendavid, Sandra ; Fargeaudou, Yann ; Portal, Jean-Jacques ; Ricbourg, Aude ; Sebbag, Delphine ; Dohan, Anthony ; Vicaut, Eric ; Soyer, Philippe</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c442t-a9de2c4bf846916dc27ea0c3e671f681c3f844a58821c239869d9a82101f94573</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Adult</topic><topic>Cesarean section</topic><topic>Diagnosis, Differential</topic><topic>Diagnostic Radiology</topic><topic>Female</topic><topic>Humans</topic><topic>Imaging</topic><topic>Internal Medicine</topic><topic>Interventional Radiology</topic><topic>Magnetic resonance imaging</topic><topic>Magnetic Resonance Imaging - methods</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Neuroradiology</topic><topic>Observer Variation</topic><topic>Placenta</topic><topic>Placenta - pathology</topic><topic>Placenta Accreta - diagnosis</topic><topic>Placenta Previa - diagnosis</topic><topic>Pregnancy</topic><topic>Pregnancy complications</topic><topic>Radiology</topic><topic>Sensitivity and Specificity</topic><topic>Ultrasonic imaging</topic><topic>Ultrasound</topic><topic>Urogenital</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bour, Laurence</creatorcontrib><creatorcontrib>Placé, Vinciane</creatorcontrib><creatorcontrib>Bendavid, Sandra</creatorcontrib><creatorcontrib>Fargeaudou, Yann</creatorcontrib><creatorcontrib>Portal, Jean-Jacques</creatorcontrib><creatorcontrib>Ricbourg, Aude</creatorcontrib><creatorcontrib>Sebbag, Delphine</creatorcontrib><creatorcontrib>Dohan, Anthony</creatorcontrib><creatorcontrib>Vicaut, Eric</creatorcontrib><creatorcontrib>Soyer, Philippe</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>European radiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bour, Laurence</au><au>Placé, Vinciane</au><au>Bendavid, Sandra</au><au>Fargeaudou, Yann</au><au>Portal, Jean-Jacques</au><au>Ricbourg, Aude</au><au>Sebbag, Delphine</au><au>Dohan, Anthony</au><au>Vicaut, Eric</au><au>Soyer, Philippe</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Suspected invasive placenta: evaluation with magnetic resonance imaging</atitle><jtitle>European radiology</jtitle><stitle>Eur Radiol</stitle><addtitle>Eur Radiol</addtitle><date>2014-12-01</date><risdate>2014</risdate><volume>24</volume><issue>12</issue><spage>3150</spage><epage>3160</epage><pages>3150-3160</pages><issn>0938-7994</issn><eissn>1432-1084</eissn><abstract>Purpose
To determine the utility of magnetic resonance imaging (MRI) in diagnosing invasive placenta (IP).
Materials and methods
MRI findings in 32 women with suspected IP were evaluated independently by four readers. Interobserver agreement was calculated with kappa (κ) statistics. Associations between MRI findings and IP were assessed by univariate and multivariate analyses. Sensitivity, specificity and accuracy of MRI for the diagnosis of IP were estimated.
Results
Sixteen women (16/32; 50 %) had confirmed IP. Interobserver correlation for the diagnosis of IP was fair (κ = 0.40). Univariate analysis revealed that thinning or focal defect of the uteroplacental interface (
P
< 0.0001) was the most discriminating MRI variable in the differentiation between normal and IP. Overall sensitivity and specificity of MRI for the diagnosis of IP were 84 % [95 % CI: 75–94 %] and 80 % [95 % CI: 66–93 %], respectively. Thinning or focal defect of the uteroplacental interface was the most accurate finding (88 %) in the diagnosis of IP. Multivariate analysis revealed that thinning or focal defect of the uteroplacental interface was the single independent predictor of IP (
P
= 0.0006; OR = 64.99).
Conclusion
MR imaging has 84 % sensitivity [95 % CI: 75–94 %] and 80 % specificity [95 % CI: 66–93 %] for the diagnosis of IP. Thinning or focal defect of the uteroplacental interface is the most discriminating independent MR variable in differentiating between normal placenta and IP.
Key points
• MR imaging has acceptable degrees of accuracy to diagnose invasive placenta.
• Focal uteroplacental interface defect is the best finding to diagnose invasive placenta.
• Focal uteroplacental interface defect is the single independent predictor of invasive placenta.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>25070274</pmid><doi>10.1007/s00330-014-3354-z</doi><tpages>11</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0938-7994 |
| ispartof | European radiology, 2014-12, Vol.24 (12), p.3150-3160 |
| issn | 0938-7994 1432-1084 |
| language | eng |
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| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Adult Cesarean section Diagnosis, Differential Diagnostic Radiology Female Humans Imaging Internal Medicine Interventional Radiology Magnetic resonance imaging Magnetic Resonance Imaging - methods Medicine Medicine & Public Health Neuroradiology Observer Variation Placenta Placenta - pathology Placenta Accreta - diagnosis Placenta Previa - diagnosis Pregnancy Pregnancy complications Radiology Sensitivity and Specificity Ultrasonic imaging Ultrasound Urogenital Young Adult |
| title | Suspected invasive placenta: evaluation with magnetic resonance imaging |
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