Biotransformation of warfarin by the fungus Beauveria bassiana

Biotransformation of racemic warfarin by the fungus Beauveria bassiana IMI 12939 was studied as part of an investigation into alternative methods for the production of drug metabolites. Resting cell suspensions in buffer were able to biotransform warfarin. High activity occurred within a broad pH ra...

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Veröffentlicht in:	Applied microbiology and biotechnology 1992-05, Vol.37 (2), p.169-175
Hauptverfasser:	GRIFFITHS, D. A, BROWN, D. E, JEZEQUEL, S. G
Format:	Artikel
Sprache:	eng
Schlagworte:	4'-hydroxywarfarin Beauveria bassiana Bioconversions. Hemisynthesis Biological and medical sciences Biotechnology Fundamental and applied biological sciences. Psychology metabolism metabolites Methods. Procedures. Technologies stereochemistry stereoisomers warfarin warfarin alpha -diketone
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