High Frequency and Clinical Prognostic Value of MYD88 L265P Mutation in Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg-Type

IMPORTANCE: The activating mutation of MYD88 L265P is a frequent feature of primary cutaneous diffuse large B-cell lymphoma, leg-type (PCLBCL-LT), reported in up to 69% of the cases. Whether patients with MYD88 mutation display specific clinical and evolutive features has not been evaluated. OBJECTI...

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Veröffentlicht in:	JAMA dermatology (Chicago, Ill.) Ill.), 2014-11, Vol.150 (11), p.1173-1179
Hauptverfasser:	Pham-Ledard, Anne, Beylot-Barry, Marie, Barbe, Coralie, Leduc, Marion, Petrella, Tony, Vergier, Béatrice, Martinez, Fabian, Cappellen, David, Merlio, Jean-Philippe, Grange, Florent
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Female Follow-Up Studies Humans Leg Lymphoma, Large B-Cell, Diffuse - genetics Lymphoma, Large B-Cell, Diffuse - pathology Male Middle Aged Multivariate Analysis Mutation Myeloid Differentiation Factor 88 - genetics NF-kappa B - metabolism Polymerase Chain Reaction Prevalence Prognosis Retrospective Studies Skin Neoplasms - genetics Skin Neoplasms - pathology Survival Rate
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