Insights into Pediatric Herpes Simplex Encephalitis From a Cohort of 21 Children From the California Encephalitis Project, 1998–2011
Twenty-one children with confirmed herpes simplex encephalitis were identified in the California Encephalitis Project. Noteworthy features included 6 (29%) patients with an initial negative herpes simplex virus cerebrospinal fluid polymerase chain reaction test and 13 (59%) patients with extratempor...
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Veröffentlicht in: | The Pediatric infectious disease journal 2014-12, Vol.33 (12), p.1287-1288 |
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creator | To, Tu M Soldatos, Ariane Sheriff, Heather Schmid, D Scott Espinosa, Natasha Cosentino, Giorgio Preas, Christopher P Glaser, Carol A |
description | Twenty-one children with confirmed herpes simplex encephalitis were identified in the California Encephalitis Project. Noteworthy features included 6 (29%) patients with an initial negative herpes simplex virus cerebrospinal fluid polymerase chain reaction test and 13 (59%) patients with extratemporal lobe involvement identified by neuroimaging. Eleven cases were |
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Noteworthy features included 6 (29%) patients with an initial negative herpes simplex virus cerebrospinal fluid polymerase chain reaction test and 13 (59%) patients with extratemporal lobe involvement identified by neuroimaging. Eleven cases were <4 years of age, but all 4 fatal cases occurred in adolescents.</description><subject>Adolescent</subject><subject>Arboviral encephalitis</subject><subject>Arboviroses</subject><subject>Biological and medical sciences</subject><subject>Brain - pathology</subject><subject>California</subject><subject>Cerebrospinal Fluid - virology</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Cohort Studies</subject><subject>Encephalitis, Herpes Simplex - pathology</subject><subject>Female</subject><subject>Human viral diseases</subject><subject>Humans</subject><subject>Infant</subject><subject>Infectious diseases</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Miscellaneous</subject><subject>Neuroimaging</subject><subject>Polymerase Chain Reaction</subject><subject>Survival Analysis</subject><subject>Tropical viral diseases</subject><subject>Viral diseases</subject><subject>Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye</subject><issn>0891-3668</issn><issn>1532-0987</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kc1u1DAQxy1ERZeWN0DIFyQOpPhrE_uIoi5dqWorQc-R1xkTFycOtleFGydeoG_YJ8Fot3wd8GEszfz-M6P5I_SckhNKVPNmfbE6IX8-wdgjtKBLziqiZPMYLYhUtOJ1LQ_R05RuCsMFJU_QIROKUqnkAn1fT8l9HHLCbsoBX0HvdI7O4DOIMyT83o2zhy_4dDIwD9q77BJexTBijdswhJhxsJhR3A7O9xGmXTEPgNtC2xAnp_9WX8VwAya_xlQpef_tjhFKj9GB1T7Bs_1_hK5Xpx_as-r88t26fXtemSVhrKIaKC-B9U0NainAihoagLrhUm9oL0wvGVEELBFGWFIbK3uyafqSkmJj-RF6tes7x_B5Cyl3o0sGvNcThG3qaF1Ow5nkpKBih5oYUopguzm6UcevHSXdTwe64kD3rwNF9mI_YbsZof8lejh5AV7uAZ2M9jbqybj0m1PFNa5E4eSOuw0-Q0yf_PYWYjeA9nn4_w4_AJV5n2U</recordid><startdate>201412</startdate><enddate>201412</enddate><creator>To, Tu M</creator><creator>Soldatos, Ariane</creator><creator>Sheriff, Heather</creator><creator>Schmid, D Scott</creator><creator>Espinosa, Natasha</creator><creator>Cosentino, Giorgio</creator><creator>Preas, Christopher P</creator><creator>Glaser, Carol A</creator><general>by Lippincott Williams & Wilkins, Inc</general><general>Lippincott Williams & Wilkins</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201412</creationdate><title>Insights into Pediatric Herpes Simplex Encephalitis From a Cohort of 21 Children From the California Encephalitis Project, 1998–2011</title><author>To, Tu M ; 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subjects | Adolescent Arboviral encephalitis Arboviroses Biological and medical sciences Brain - pathology California Cerebrospinal Fluid - virology Child Child, Preschool Cohort Studies Encephalitis, Herpes Simplex - pathology Female Human viral diseases Humans Infant Infectious diseases Male Medical sciences Miscellaneous Neuroimaging Polymerase Chain Reaction Survival Analysis Tropical viral diseases Viral diseases Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye |
title | Insights into Pediatric Herpes Simplex Encephalitis From a Cohort of 21 Children From the California Encephalitis Project, 1998–2011 |
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