Modulation of TCDD-induced fetotoxicity and oxidative stress in embryonic and placental tissues of C57BL/6J mice by vitamin E succinate and ellagic acid

The ability of vitamin E succinate and ellagic acid to modulate 2,3,7,8-tetrachlorodibenzo- p-dioxin (TCDD)-induced developmental toxicity and oxidative damage in embryonic/fetal and placental tissues was studied in C57BL/6J mice. Vitamin E succinate (100 mg/kg per day) and ellagic acid(6 mg/kg per...

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Veröffentlicht in:	Toxicology (Amsterdam) 1997-12, Vol.124 (1), p.27-37
Hauptverfasser:	Hassoun, E.A, Walter, A.C, Alsharif, N.Z, Stohs, S.J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences C57BL/6J mice Chemical and industrial products toxicology. Toxic occupational diseases DNA Damage Ellagic acid Ellagic Acid - pharmacology Embryology: invertebrates and vertebrates. Teratology Female Fetotoxicity Fetus Fetus - drug effects Fetus - metabolism Fundamental and applied biological sciences. Psychology Lipid Peroxidation Male Medical sciences Mice Mice, Inbred C57BL Oxidative Stress Placenta Placenta - drug effects Placenta - metabolism Polychlorinated Dibenzodioxins - toxicity Pregnancy TCDD Teratology. Teratogens Tocopherols Toxicology Various organic compounds Vitamin E - analogs & derivatives Vitamin E - pharmacology Vitamin E succinate
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