Loss of the xeroderma pigmentosum group A gene (XPA) enhances apoptosis of cultured cerebellar neurons induced by UV but not by low-K super(+) medium

To study the involvement of the xeroderma pigmentosum group A gene (XPA) in neuronal apoptosis, we cultured cerebellar neurons from mice lacking XPA gene (XPA super(-/-)) and induced apoptosis by exposure to UV irradiation or medium containing a low concentration of potassium (low-K super(+) medium)...

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Veröffentlicht in:	Journal of neurochemistry 1997-07, Vol.69 (1), p.246-251
Hauptverfasser:	Enokido, Y, Inamura, N, Araki, T, Satoh, T, Nakane, H, Yoshino, M, Nakatsu, Y, Tanaka, K, Hatanaka, H
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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