Development of the B cell anti-DNA repertoire in (NZB x NZW)F sub(1) mice. Relationship with the natural autoimmune repertoire

The relationship between pathologic anti-DNA and natural autoantibodies (Auto Ab) remains unclear. In particular, it has not yet been elucidated whether pathologic anti-DNA antibodies originate from and are regulated by the pool of natural Auto Ab. To address this question, a large number of Ig-secr...

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Veröffentlicht in:The Journal of immunology (1950) 1992-01, Vol.149 (5), p.1795-1801
Hauptverfasser: Gilbert, D, Margaritte, C, Payelle-Brogart, B, Tron, F
Format: Artikel
Sprache:eng
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