Long-term results of sequential vein coronary artery bypass grafting compared with totally arterial myocardial revascularization: a propensity score-matched follow-up study
The aim of the study was to analyse the early and long-term outcomes of a consecutive series of patients who underwent sequential coronary artery bypass grafting (CABG) and to compare them with a matched population of totally arterial revascularized patients. From January 1994 to December 1996, 209...
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Veröffentlicht in: | European journal of cardio-thoracic surgery 2014-12, Vol.46 (6), p.1006-1013 |
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creator | Garatti, Andrea Castelvecchio, Serenella Canziani, Alberto Corain, Livio Generali, Tommaso Mossuto, Eugenio Gagliardotto, Piervincenzo Anastasia, Luigi Salmaso, Luigi Giacomazzi, Francesca Menicanti, Lorenzo |
description | The aim of the study was to analyse the early and long-term outcomes of a consecutive series of patients who underwent sequential coronary artery bypass grafting (CABG) and to compare them with a matched population of totally arterial revascularized patients.
From January 1994 to December 1996, 209 patients underwent total arterial myocardial revascularization at our institution [arterial (ART) group]. In the same period, 2097 patients underwent CABG with left internal thoracic artery on left anterior descending and great saphenous vein on the right and circumflex branches sequentially [sequential vein (SV) group]. The propensity score methodology was used to obtain risk-adjusted outcome comparisons between the two groups (209 vs 243 patients in the ART group and SV group, respectively).
In-hospital mortality was 1% in the ART group and 0.4% in the SV group (P = 0.86). Mean follow-up was 14 ± 4 years. Long-term survival was comparable among the two study groups [actuarial 5- and 15-year survival rates were 97 vs 93% and 82 vs 79% in the ART group and the SV group, respectively (P = 0.29)]. At follow-up, recurrence of angina (17 vs 18%; P = 0.99), acute myocardial infarction (MI) (3 vs 5%; P = 0.72) and repeated percutaneous coronary intervention (19 vs 21%; P = 0.69) were similar in the ART group compared with the SV group. In the Cox regression analysis, type of revascularization was not an independent predictor of any long-term outcomes (death or major adverse cardiac events). In asymptomatic patients, exercise stress test at follow-up was comparable between the two groups (P = 0.14).
Sequential vein CABG appears to have good early and long-term clinical outcomes. Also, early and long-term incidence of acute MI was not significantly higher in the SV group. However, further studies with a larger population are warranted in order to confirm the present results. |
doi_str_mv | 10.1093/ejcts/ezu057 |
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From January 1994 to December 1996, 209 patients underwent total arterial myocardial revascularization at our institution [arterial (ART) group]. In the same period, 2097 patients underwent CABG with left internal thoracic artery on left anterior descending and great saphenous vein on the right and circumflex branches sequentially [sequential vein (SV) group]. The propensity score methodology was used to obtain risk-adjusted outcome comparisons between the two groups (209 vs 243 patients in the ART group and SV group, respectively).
In-hospital mortality was 1% in the ART group and 0.4% in the SV group (P = 0.86). Mean follow-up was 14 ± 4 years. Long-term survival was comparable among the two study groups [actuarial 5- and 15-year survival rates were 97 vs 93% and 82 vs 79% in the ART group and the SV group, respectively (P = 0.29)]. At follow-up, recurrence of angina (17 vs 18%; P = 0.99), acute myocardial infarction (MI) (3 vs 5%; P = 0.72) and repeated percutaneous coronary intervention (19 vs 21%; P = 0.69) were similar in the ART group compared with the SV group. In the Cox regression analysis, type of revascularization was not an independent predictor of any long-term outcomes (death or major adverse cardiac events). In asymptomatic patients, exercise stress test at follow-up was comparable between the two groups (P = 0.14).
Sequential vein CABG appears to have good early and long-term clinical outcomes. Also, early and long-term incidence of acute MI was not significantly higher in the SV group. However, further studies with a larger population are warranted in order to confirm the present results.</description><identifier>ISSN: 1010-7940</identifier><identifier>EISSN: 1873-734X</identifier><identifier>DOI: 10.1093/ejcts/ezu057</identifier><identifier>PMID: 24627440</identifier><language>eng</language><publisher>Germany</publisher><subject>Angina Pectoris - surgery ; Blood Vessel Prosthesis ; Coronary Artery Bypass - methods ; Coronary Artery Bypass - mortality ; Exercise Test ; Female ; Follow-Up Studies ; Hospital Mortality ; Humans ; Italy - epidemiology ; Kaplan-Meier Estimate ; Male ; Middle Aged ; Myocardial Ischemia - surgery ; Myocardial Revascularization - methods ; Myocardial Revascularization - mortality ; Propensity Score ; Retrospective Studies ; Treatment Outcome</subject><ispartof>European journal of cardio-thoracic surgery, 2014-12, Vol.46 (6), p.1006-1013</ispartof><rights>The Author 2014. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c329t-e93e72188bd58f72f22a600d5abebfc98af0659ad8c3673ed559905ebf1776723</citedby><cites>FETCH-LOGICAL-c329t-e93e72188bd58f72f22a600d5abebfc98af0659ad8c3673ed559905ebf1776723</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24627440$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Garatti, Andrea</creatorcontrib><creatorcontrib>Castelvecchio, Serenella</creatorcontrib><creatorcontrib>Canziani, Alberto</creatorcontrib><creatorcontrib>Corain, Livio</creatorcontrib><creatorcontrib>Generali, Tommaso</creatorcontrib><creatorcontrib>Mossuto, Eugenio</creatorcontrib><creatorcontrib>Gagliardotto, Piervincenzo</creatorcontrib><creatorcontrib>Anastasia, Luigi</creatorcontrib><creatorcontrib>Salmaso, Luigi</creatorcontrib><creatorcontrib>Giacomazzi, Francesca</creatorcontrib><creatorcontrib>Menicanti, Lorenzo</creatorcontrib><title>Long-term results of sequential vein coronary artery bypass grafting compared with totally arterial myocardial revascularization: a propensity score-matched follow-up study</title><title>European journal of cardio-thoracic surgery</title><addtitle>Eur J Cardiothorac Surg</addtitle><description>The aim of the study was to analyse the early and long-term outcomes of a consecutive series of patients who underwent sequential coronary artery bypass grafting (CABG) and to compare them with a matched population of totally arterial revascularized patients.
From January 1994 to December 1996, 209 patients underwent total arterial myocardial revascularization at our institution [arterial (ART) group]. In the same period, 2097 patients underwent CABG with left internal thoracic artery on left anterior descending and great saphenous vein on the right and circumflex branches sequentially [sequential vein (SV) group]. The propensity score methodology was used to obtain risk-adjusted outcome comparisons between the two groups (209 vs 243 patients in the ART group and SV group, respectively).
In-hospital mortality was 1% in the ART group and 0.4% in the SV group (P = 0.86). Mean follow-up was 14 ± 4 years. Long-term survival was comparable among the two study groups [actuarial 5- and 15-year survival rates were 97 vs 93% and 82 vs 79% in the ART group and the SV group, respectively (P = 0.29)]. At follow-up, recurrence of angina (17 vs 18%; P = 0.99), acute myocardial infarction (MI) (3 vs 5%; P = 0.72) and repeated percutaneous coronary intervention (19 vs 21%; P = 0.69) were similar in the ART group compared with the SV group. In the Cox regression analysis, type of revascularization was not an independent predictor of any long-term outcomes (death or major adverse cardiac events). In asymptomatic patients, exercise stress test at follow-up was comparable between the two groups (P = 0.14).
Sequential vein CABG appears to have good early and long-term clinical outcomes. Also, early and long-term incidence of acute MI was not significantly higher in the SV group. However, further studies with a larger population are warranted in order to confirm the present results.</description><subject>Angina Pectoris - surgery</subject><subject>Blood Vessel Prosthesis</subject><subject>Coronary Artery Bypass - methods</subject><subject>Coronary Artery Bypass - mortality</subject><subject>Exercise Test</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Hospital Mortality</subject><subject>Humans</subject><subject>Italy - epidemiology</subject><subject>Kaplan-Meier Estimate</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Myocardial Ischemia - surgery</subject><subject>Myocardial Revascularization - methods</subject><subject>Myocardial Revascularization - mortality</subject><subject>Propensity Score</subject><subject>Retrospective Studies</subject><subject>Treatment Outcome</subject><issn>1010-7940</issn><issn>1873-734X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kUFv1DAQhS0EoqVw44x85ECoYydxwg1VhVZaiQtI3KKJM966cuLgcVqlv4kfiZddOM1I79N7o3mMvS3Fx1J06hLvTaJLfFpFrZ-x87LVqtCq-vk876IUhe4qccZeEd0LIRol9Ut2JqtG6qoS5-z3Lsz7ImGceERafSIeLCf8teKcHHj-gG7mJsQwQ9w4xIxufNgWIOL7CDa5eZ_1aYGII3906Y6nkMD7E3zwmLZgII6HNeIDkFk9RPcEyYX5Ewe-xLDgTC5tnHIUFhMkc5ftbPA-PBbrwimt4_aavbDgCd-c5gX78eX6-9VNsfv29fbq864wSnapwE6hlmXbDmPdWi2tlNAIMdYw4GBN14IVTd3B2BrVaIVjXXedqLNWat1oqS7Y-6NvPiw_glI_OTLoPcwYVurLRuagWlUqox-OqImBKKLtl-im_Kq-FP2hn_5vP_2xn4y_Ozmvw4Tjf_hfIeoP74uT6A</recordid><startdate>201412</startdate><enddate>201412</enddate><creator>Garatti, Andrea</creator><creator>Castelvecchio, Serenella</creator><creator>Canziani, Alberto</creator><creator>Corain, Livio</creator><creator>Generali, Tommaso</creator><creator>Mossuto, Eugenio</creator><creator>Gagliardotto, Piervincenzo</creator><creator>Anastasia, Luigi</creator><creator>Salmaso, Luigi</creator><creator>Giacomazzi, Francesca</creator><creator>Menicanti, Lorenzo</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201412</creationdate><title>Long-term results of sequential vein coronary artery bypass grafting compared with totally arterial myocardial revascularization: a propensity score-matched follow-up study</title><author>Garatti, Andrea ; Castelvecchio, Serenella ; Canziani, Alberto ; Corain, Livio ; Generali, Tommaso ; Mossuto, Eugenio ; Gagliardotto, Piervincenzo ; Anastasia, Luigi ; Salmaso, Luigi ; Giacomazzi, Francesca ; Menicanti, Lorenzo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c329t-e93e72188bd58f72f22a600d5abebfc98af0659ad8c3673ed559905ebf1776723</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Angina Pectoris - surgery</topic><topic>Blood Vessel Prosthesis</topic><topic>Coronary Artery Bypass - methods</topic><topic>Coronary Artery Bypass - mortality</topic><topic>Exercise Test</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Hospital Mortality</topic><topic>Humans</topic><topic>Italy - epidemiology</topic><topic>Kaplan-Meier Estimate</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Myocardial Ischemia - surgery</topic><topic>Myocardial Revascularization - methods</topic><topic>Myocardial Revascularization - mortality</topic><topic>Propensity Score</topic><topic>Retrospective Studies</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Garatti, Andrea</creatorcontrib><creatorcontrib>Castelvecchio, Serenella</creatorcontrib><creatorcontrib>Canziani, Alberto</creatorcontrib><creatorcontrib>Corain, Livio</creatorcontrib><creatorcontrib>Generali, Tommaso</creatorcontrib><creatorcontrib>Mossuto, Eugenio</creatorcontrib><creatorcontrib>Gagliardotto, Piervincenzo</creatorcontrib><creatorcontrib>Anastasia, Luigi</creatorcontrib><creatorcontrib>Salmaso, Luigi</creatorcontrib><creatorcontrib>Giacomazzi, Francesca</creatorcontrib><creatorcontrib>Menicanti, Lorenzo</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of cardio-thoracic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Garatti, Andrea</au><au>Castelvecchio, Serenella</au><au>Canziani, Alberto</au><au>Corain, Livio</au><au>Generali, Tommaso</au><au>Mossuto, Eugenio</au><au>Gagliardotto, Piervincenzo</au><au>Anastasia, Luigi</au><au>Salmaso, Luigi</au><au>Giacomazzi, Francesca</au><au>Menicanti, Lorenzo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Long-term results of sequential vein coronary artery bypass grafting compared with totally arterial myocardial revascularization: a propensity score-matched follow-up study</atitle><jtitle>European journal of cardio-thoracic surgery</jtitle><addtitle>Eur J Cardiothorac Surg</addtitle><date>2014-12</date><risdate>2014</risdate><volume>46</volume><issue>6</issue><spage>1006</spage><epage>1013</epage><pages>1006-1013</pages><issn>1010-7940</issn><eissn>1873-734X</eissn><abstract>The aim of the study was to analyse the early and long-term outcomes of a consecutive series of patients who underwent sequential coronary artery bypass grafting (CABG) and to compare them with a matched population of totally arterial revascularized patients.
From January 1994 to December 1996, 209 patients underwent total arterial myocardial revascularization at our institution [arterial (ART) group]. In the same period, 2097 patients underwent CABG with left internal thoracic artery on left anterior descending and great saphenous vein on the right and circumflex branches sequentially [sequential vein (SV) group]. The propensity score methodology was used to obtain risk-adjusted outcome comparisons between the two groups (209 vs 243 patients in the ART group and SV group, respectively).
In-hospital mortality was 1% in the ART group and 0.4% in the SV group (P = 0.86). Mean follow-up was 14 ± 4 years. Long-term survival was comparable among the two study groups [actuarial 5- and 15-year survival rates were 97 vs 93% and 82 vs 79% in the ART group and the SV group, respectively (P = 0.29)]. At follow-up, recurrence of angina (17 vs 18%; P = 0.99), acute myocardial infarction (MI) (3 vs 5%; P = 0.72) and repeated percutaneous coronary intervention (19 vs 21%; P = 0.69) were similar in the ART group compared with the SV group. In the Cox regression analysis, type of revascularization was not an independent predictor of any long-term outcomes (death or major adverse cardiac events). In asymptomatic patients, exercise stress test at follow-up was comparable between the two groups (P = 0.14).
Sequential vein CABG appears to have good early and long-term clinical outcomes. Also, early and long-term incidence of acute MI was not significantly higher in the SV group. However, further studies with a larger population are warranted in order to confirm the present results.</abstract><cop>Germany</cop><pmid>24627440</pmid><doi>10.1093/ejcts/ezu057</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Angina Pectoris - surgery Blood Vessel Prosthesis Coronary Artery Bypass - methods Coronary Artery Bypass - mortality Exercise Test Female Follow-Up Studies Hospital Mortality Humans Italy - epidemiology Kaplan-Meier Estimate Male Middle Aged Myocardial Ischemia - surgery Myocardial Revascularization - methods Myocardial Revascularization - mortality Propensity Score Retrospective Studies Treatment Outcome |
title | Long-term results of sequential vein coronary artery bypass grafting compared with totally arterial myocardial revascularization: a propensity score-matched follow-up study |
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