Normalization of nano-sized TiO2-induced clastogenicity, genotoxicity and mutagenicity by chlorophyllin administration in mice brain, liver, and bone marrow cells

The intensive uses of titanium dioxide (TiO2) nanoparticles in sunscreens, toothpaste, sweats, medications, etc. making humans exposed to it daily by not little amounts and also increased its risks including genotoxicity. Thus, the present study was designed as one way to reduce nano-titanium-induce...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Toxicological sciences 2014-11, Vol.142 (1), p.21-32
Hauptverfasser:	El-Ghor, Akmal A, Noshy, Magda M, Galal, Ahmad, Mohamed, Hanan Ramadan H
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bone Marrow Cells - drug effects Bone Marrow Cells - metabolism Bone Marrow Cells - pathology Brain - drug effects Brain - metabolism Brain - pathology Chlorophyllides - pharmacology Comet Assay DNA Damage - drug effects Free Radical Scavengers - administration & dosage Free Radical Scavengers - pharmacology Liver - drug effects Liver - metabolism Liver - pathology Male Mice, Inbred Strains Micronuclei, Chromosome-Defective - chemically induced Micronuclei, Chromosome-Defective - drug effects Micronucleus Tests Mutagens - administration & dosage Mutagens - chemistry Mutagens - toxicity Mutation Nanoparticles Oxidative Stress - drug effects Oxidative Stress - genetics Titanium - administration & dosage Titanium - chemistry Titanium - toxicity Tumor Suppressor Protein p53 - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!