HIV-1 capsid mutants inhibit the replication of wild-type virus at both early and late infection phases

In-frame mutations were introduced into various portions of the human immunodeficiency virus type 1 (HIV-1) gag gene, and potentials of the mutants to suppress the replication of wild-type HIV-1 were monitored. In contrast to results obtained with matrix and nucleocapsid mutants, almost all capsid m...

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Veröffentlicht in:	FEBS letters 1997-09, Vol.415 (2), p.231-234
Hauptverfasser:	Furuta, Rika A, Shimano, Reika, Ogasawara, Takashi, Inubushi, Ritsuko, Amano, Kazushi, Akari, Hirofumi, Hatanaka, Masakazu, Kawamura, Meiko, Adachi, Akio
Format:	Artikel
Sprache:	eng
Schlagworte:	Blotting, Western Capsid Capsid - chemistry Capsid - genetics Capsid - physiology CD4-Positive T-Lymphocytes - virology Chloramphenicol O-Acetyltransferase - genetics Chloramphenicol O-Acetyltransferase - metabolism Gag Gene Expression Gene Products, gag - genetics Gene Products, gag - physiology Genes, gag Genetic Vectors HIV-1 - genetics HIV-1 - physiology Human immunodeficiency virus type 1 Humans Matrix Mutagenesis Mutation Nucleocapsid Transfection Tumor Cells, Cultured Virus Replication
Online-Zugang:	Volltext
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