Orbital bleeding in rats while under diethylether anaesthesia does not influence telemetrically determined heart rate, body temperature, locomotor and eating activity when compared with anaesthesia alone
The question addressed was whether orbital bleeding in rats, while under diethylether anaesthesia, affects their locomotor activity, body core temperature, heart rate rhythm and eating pattern. Roman High Avoidance (RHA) and Roman Low Avoidance (RLA) rats were used to enhance generalization of the r...
Gespeichert in:
| Veröffentlicht in: | Laboratory animals (London) 1997-07, Vol.31 (3), p.271-278 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 278 |
|---|---|
| container_issue | 3 |
| container_start_page | 271 |
| container_title | Laboratory animals (London) |
| container_volume | 31 |
| creator | Herck, H. van Boer, S.F. de Hesp, A.P.M Lith, H.A. van Baumans, V Beynen, A.C |
| description | The question addressed was whether orbital bleeding in rats, while under diethylether anaesthesia, affects their locomotor activity, body core temperature, heart rate rhythm and eating pattern. Roman High Avoidance (RHA) and Roman Low Avoidance (RLA) rats were used to enhance generalization of the results. Orbital bleeding when the rats were under diethylether anaesthesia was compared with diethylether anaesthesia alone. To take into account any effects of handling, the rats were also subjected to sham anaesthesia. The RHA rats urinated more during anaesthesia, needed more time to recover from the anaesthesia and showed a greater endocrine stress response to diethylether anaesthesia when compared with the RLA rats. During anaesthesia, the RHA rats showed a greater fall of body temperature and bradycardia than did the RLA rats. Diethylether anaesthesia reduced locomotor activity in the RHA rats, but had no effect in the RLA rats. In neither RHA nor RLA rats did anaesthesia plus orbital puncture, versus anaesthesia alone, influence body temperature, heart rate rhythm, locomotor and eating activity. The lack of effect of orbital puncture occurred both in the short term (within 2h) and long term (within 48 hours) and thus this study indicates that orbital puncture had, at least with respect to variables measured in the present study, no effect superimposed on that of diethylether anaesthesia. |
| doi_str_mv | 10.1258/002367797780596284 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_16230877</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sage_id>10.1258_002367797780596284</sage_id><sourcerecordid>16230877</sourcerecordid><originalsourceid>FETCH-LOGICAL-c437t-ae4c168a6eca271ba728d7635ea9531e6db7d2f6704c4b9cde1337e86b48653e3</originalsourceid><addsrcrecordid>eNp9UcuKFDEULUQZ29EfEMSsXFlOHlVJaimDLxiYhc66uJXc6s6QStokNUN_oz9lmm4EEdwkObnnnHuS2zSvGf3AeK-vKOVCKjUopWk_SK67J82GqV63jDH1tNkcCW1l8OfNi5zvK2SdphfNxcAF7emwaX7dpskV8GTyiNaFLXGBJCiZPO6cR7IGi4lYh2V38HWpAAJgrqfsgNiImYRYqmr2KwaDpKDHBUtyBrw_EIsF0-ICWrJDSOVoju_JFO2hUpc9VrymeuOjiUss8djAEoRyDAOmuAdXDjUNBlIJe0jV6dGV3V85wMeAL5tnM_iMr877ZXP3-dOP66_tze2Xb9cfb1rTCVVawM4wqUGiAa7YBIprq6ToEYZeMJR2UpbPUtHOdNNgLDIhFGo5dVr2AsVl8-7ku0_x51ozjIvLBr2HgHHNI5P1d7VSlchPRJNizgnncZ_cAukwMjoeJzj-O8EqenN2X6cF7R_JeWS1fnWqZ9jieB_XFOpj_-_49qSYIY6wTS6Pd985ZYJyLYdeduI3GA2zTg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>16230877</pqid></control><display><type>article</type><title>Orbital bleeding in rats while under diethylether anaesthesia does not influence telemetrically determined heart rate, body temperature, locomotor and eating activity when compared with anaesthesia alone</title><source>MEDLINE</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>Herck, H. van ; Boer, S.F. de ; Hesp, A.P.M ; Lith, H.A. van ; Baumans, V ; Beynen, A.C</creator><creatorcontrib>Herck, H. van ; Boer, S.F. de ; Hesp, A.P.M ; Lith, H.A. van ; Baumans, V ; Beynen, A.C</creatorcontrib><description>The question addressed was whether orbital bleeding in rats, while under diethylether anaesthesia, affects their locomotor activity, body core temperature, heart rate rhythm and eating pattern. Roman High Avoidance (RHA) and Roman Low Avoidance (RLA) rats were used to enhance generalization of the results. Orbital bleeding when the rats were under diethylether anaesthesia was compared with diethylether anaesthesia alone. To take into account any effects of handling, the rats were also subjected to sham anaesthesia. The RHA rats urinated more during anaesthesia, needed more time to recover from the anaesthesia and showed a greater endocrine stress response to diethylether anaesthesia when compared with the RLA rats. During anaesthesia, the RHA rats showed a greater fall of body temperature and bradycardia than did the RLA rats. Diethylether anaesthesia reduced locomotor activity in the RHA rats, but had no effect in the RLA rats. In neither RHA nor RLA rats did anaesthesia plus orbital puncture, versus anaesthesia alone, influence body temperature, heart rate rhythm, locomotor and eating activity. The lack of effect of orbital puncture occurred both in the short term (within 2h) and long term (within 48 hours) and thus this study indicates that orbital puncture had, at least with respect to variables measured in the present study, no effect superimposed on that of diethylether anaesthesia.</description><identifier>ISSN: 0023-6772</identifier><identifier>EISSN: 1758-1117</identifier><identifier>DOI: 10.1258/002367797780596284</identifier><identifier>PMID: 9230509</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>anesthesia ; Anesthesia - adverse effects ; Anesthesia - veterinary ; Anesthetics, Inhalation - adverse effects ; animal experimentation ; Animals ; behavior ; Blood Glucose - analysis ; Blood Specimen Collection - adverse effects ; Blood Specimen Collection - methods ; Blood Specimen Collection - veterinary ; body temperature ; Body Temperature - physiology ; Corticosterone - blood ; Eating - physiology ; eating habits ; Epinephrine - blood ; Ether - adverse effects ; ethyl ether ; heart rate ; Heart Rate - physiology ; hemorrhage ; lines ; locomotion ; Male ; Motor Activity - physiology ; Norepinephrine - blood ; Orbit ; orbits ; Rats ; stress ; Telemetry - veterinary</subject><ispartof>Laboratory animals (London), 1997-07, Vol.31 (3), p.271-278</ispartof><rights>1997 Royal Society of Medicine Press</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c437t-ae4c168a6eca271ba728d7635ea9531e6db7d2f6704c4b9cde1337e86b48653e3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9230509$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Herck, H. van</creatorcontrib><creatorcontrib>Boer, S.F. de</creatorcontrib><creatorcontrib>Hesp, A.P.M</creatorcontrib><creatorcontrib>Lith, H.A. van</creatorcontrib><creatorcontrib>Baumans, V</creatorcontrib><creatorcontrib>Beynen, A.C</creatorcontrib><title>Orbital bleeding in rats while under diethylether anaesthesia does not influence telemetrically determined heart rate, body temperature, locomotor and eating activity when compared with anaesthesia alone</title><title>Laboratory animals (London)</title><addtitle>Lab Anim</addtitle><description>The question addressed was whether orbital bleeding in rats, while under diethylether anaesthesia, affects their locomotor activity, body core temperature, heart rate rhythm and eating pattern. Roman High Avoidance (RHA) and Roman Low Avoidance (RLA) rats were used to enhance generalization of the results. Orbital bleeding when the rats were under diethylether anaesthesia was compared with diethylether anaesthesia alone. To take into account any effects of handling, the rats were also subjected to sham anaesthesia. The RHA rats urinated more during anaesthesia, needed more time to recover from the anaesthesia and showed a greater endocrine stress response to diethylether anaesthesia when compared with the RLA rats. During anaesthesia, the RHA rats showed a greater fall of body temperature and bradycardia than did the RLA rats. Diethylether anaesthesia reduced locomotor activity in the RHA rats, but had no effect in the RLA rats. In neither RHA nor RLA rats did anaesthesia plus orbital puncture, versus anaesthesia alone, influence body temperature, heart rate rhythm, locomotor and eating activity. The lack of effect of orbital puncture occurred both in the short term (within 2h) and long term (within 48 hours) and thus this study indicates that orbital puncture had, at least with respect to variables measured in the present study, no effect superimposed on that of diethylether anaesthesia.</description><subject>anesthesia</subject><subject>Anesthesia - adverse effects</subject><subject>Anesthesia - veterinary</subject><subject>Anesthetics, Inhalation - adverse effects</subject><subject>animal experimentation</subject><subject>Animals</subject><subject>behavior</subject><subject>Blood Glucose - analysis</subject><subject>Blood Specimen Collection - adverse effects</subject><subject>Blood Specimen Collection - methods</subject><subject>Blood Specimen Collection - veterinary</subject><subject>body temperature</subject><subject>Body Temperature - physiology</subject><subject>Corticosterone - blood</subject><subject>Eating - physiology</subject><subject>eating habits</subject><subject>Epinephrine - blood</subject><subject>Ether - adverse effects</subject><subject>ethyl ether</subject><subject>heart rate</subject><subject>Heart Rate - physiology</subject><subject>hemorrhage</subject><subject>lines</subject><subject>locomotion</subject><subject>Male</subject><subject>Motor Activity - physiology</subject><subject>Norepinephrine - blood</subject><subject>Orbit</subject><subject>orbits</subject><subject>Rats</subject><subject>stress</subject><subject>Telemetry - veterinary</subject><issn>0023-6772</issn><issn>1758-1117</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9UcuKFDEULUQZ29EfEMSsXFlOHlVJaimDLxiYhc66uJXc6s6QStokNUN_oz9lmm4EEdwkObnnnHuS2zSvGf3AeK-vKOVCKjUopWk_SK67J82GqV63jDH1tNkcCW1l8OfNi5zvK2SdphfNxcAF7emwaX7dpskV8GTyiNaFLXGBJCiZPO6cR7IGi4lYh2V38HWpAAJgrqfsgNiImYRYqmr2KwaDpKDHBUtyBrw_EIsF0-ICWrJDSOVoju_JFO2hUpc9VrymeuOjiUss8djAEoRyDAOmuAdXDjUNBlIJe0jV6dGV3V85wMeAL5tnM_iMr877ZXP3-dOP66_tze2Xb9cfb1rTCVVawM4wqUGiAa7YBIprq6ToEYZeMJR2UpbPUtHOdNNgLDIhFGo5dVr2AsVl8-7ku0_x51ozjIvLBr2HgHHNI5P1d7VSlchPRJNizgnncZ_cAukwMjoeJzj-O8EqenN2X6cF7R_JeWS1fnWqZ9jieB_XFOpj_-_49qSYIY6wTS6Pd985ZYJyLYdeduI3GA2zTg</recordid><startdate>19970701</startdate><enddate>19970701</enddate><creator>Herck, H. van</creator><creator>Boer, S.F. de</creator><creator>Hesp, A.P.M</creator><creator>Lith, H.A. van</creator><creator>Baumans, V</creator><creator>Beynen, A.C</creator><general>SAGE Publications</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QG</scope></search><sort><creationdate>19970701</creationdate><title>Orbital bleeding in rats while under diethylether anaesthesia does not influence telemetrically determined heart rate, body temperature, locomotor and eating activity when compared with anaesthesia alone</title><author>Herck, H. van ; Boer, S.F. de ; Hesp, A.P.M ; Lith, H.A. van ; Baumans, V ; Beynen, A.C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c437t-ae4c168a6eca271ba728d7635ea9531e6db7d2f6704c4b9cde1337e86b48653e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>anesthesia</topic><topic>Anesthesia - adverse effects</topic><topic>Anesthesia - veterinary</topic><topic>Anesthetics, Inhalation - adverse effects</topic><topic>animal experimentation</topic><topic>Animals</topic><topic>behavior</topic><topic>Blood Glucose - analysis</topic><topic>Blood Specimen Collection - adverse effects</topic><topic>Blood Specimen Collection - methods</topic><topic>Blood Specimen Collection - veterinary</topic><topic>body temperature</topic><topic>Body Temperature - physiology</topic><topic>Corticosterone - blood</topic><topic>Eating - physiology</topic><topic>eating habits</topic><topic>Epinephrine - blood</topic><topic>Ether - adverse effects</topic><topic>ethyl ether</topic><topic>heart rate</topic><topic>Heart Rate - physiology</topic><topic>hemorrhage</topic><topic>lines</topic><topic>locomotion</topic><topic>Male</topic><topic>Motor Activity - physiology</topic><topic>Norepinephrine - blood</topic><topic>Orbit</topic><topic>orbits</topic><topic>Rats</topic><topic>stress</topic><topic>Telemetry - veterinary</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Herck, H. van</creatorcontrib><creatorcontrib>Boer, S.F. de</creatorcontrib><creatorcontrib>Hesp, A.P.M</creatorcontrib><creatorcontrib>Lith, H.A. van</creatorcontrib><creatorcontrib>Baumans, V</creatorcontrib><creatorcontrib>Beynen, A.C</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Animal Behavior Abstracts</collection><jtitle>Laboratory animals (London)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Herck, H. van</au><au>Boer, S.F. de</au><au>Hesp, A.P.M</au><au>Lith, H.A. van</au><au>Baumans, V</au><au>Beynen, A.C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Orbital bleeding in rats while under diethylether anaesthesia does not influence telemetrically determined heart rate, body temperature, locomotor and eating activity when compared with anaesthesia alone</atitle><jtitle>Laboratory animals (London)</jtitle><addtitle>Lab Anim</addtitle><date>1997-07-01</date><risdate>1997</risdate><volume>31</volume><issue>3</issue><spage>271</spage><epage>278</epage><pages>271-278</pages><issn>0023-6772</issn><eissn>1758-1117</eissn><abstract>The question addressed was whether orbital bleeding in rats, while under diethylether anaesthesia, affects their locomotor activity, body core temperature, heart rate rhythm and eating pattern. Roman High Avoidance (RHA) and Roman Low Avoidance (RLA) rats were used to enhance generalization of the results. Orbital bleeding when the rats were under diethylether anaesthesia was compared with diethylether anaesthesia alone. To take into account any effects of handling, the rats were also subjected to sham anaesthesia. The RHA rats urinated more during anaesthesia, needed more time to recover from the anaesthesia and showed a greater endocrine stress response to diethylether anaesthesia when compared with the RLA rats. During anaesthesia, the RHA rats showed a greater fall of body temperature and bradycardia than did the RLA rats. Diethylether anaesthesia reduced locomotor activity in the RHA rats, but had no effect in the RLA rats. In neither RHA nor RLA rats did anaesthesia plus orbital puncture, versus anaesthesia alone, influence body temperature, heart rate rhythm, locomotor and eating activity. The lack of effect of orbital puncture occurred both in the short term (within 2h) and long term (within 48 hours) and thus this study indicates that orbital puncture had, at least with respect to variables measured in the present study, no effect superimposed on that of diethylether anaesthesia.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>9230509</pmid><doi>10.1258/002367797780596284</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0023-6772 |
| ispartof | Laboratory animals (London), 1997-07, Vol.31 (3), p.271-278 |
| issn | 0023-6772 1758-1117 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_16230877 |
| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | anesthesia Anesthesia - adverse effects Anesthesia - veterinary Anesthetics, Inhalation - adverse effects animal experimentation Animals behavior Blood Glucose - analysis Blood Specimen Collection - adverse effects Blood Specimen Collection - methods Blood Specimen Collection - veterinary body temperature Body Temperature - physiology Corticosterone - blood Eating - physiology eating habits Epinephrine - blood Ether - adverse effects ethyl ether heart rate Heart Rate - physiology hemorrhage lines locomotion Male Motor Activity - physiology Norepinephrine - blood Orbit orbits Rats stress Telemetry - veterinary |
| title | Orbital bleeding in rats while under diethylether anaesthesia does not influence telemetrically determined heart rate, body temperature, locomotor and eating activity when compared with anaesthesia alone |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-02T06%3A57%3A26IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Orbital%20bleeding%20in%20rats%20while%20under%20diethylether%20anaesthesia%20does%20not%20influence%20telemetrically%20determined%20heart%20rate,%20body%20temperature,%20locomotor%20and%20eating%20activity%20when%20compared%20with%20anaesthesia%20alone&rft.jtitle=Laboratory%20animals%20(London)&rft.au=Herck,%20H.%20van&rft.date=1997-07-01&rft.volume=31&rft.issue=3&rft.spage=271&rft.epage=278&rft.pages=271-278&rft.issn=0023-6772&rft.eissn=1758-1117&rft_id=info:doi/10.1258/002367797780596284&rft_dat=%3Cproquest_cross%3E16230877%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=16230877&rft_id=info:pmid/9230509&rft_sage_id=10.1258_002367797780596284&rfr_iscdi=true |