Antibacterial activity of N-(2-(dodecanoyl-methylamine)ethyl)-alkyldimethylammonium bromides

Antibacterial activity of N-(2-(dodecanoyl-methylamine)ethyl)-alkyldimethylammonium bromides

The study contains the results of determination of antibacteria of the newly synthesized series of N-(2-(dodecanoyl-methylamine)ethyl)-alkyldimethylammonium bromides. The efficiency of the compounds has been characterized towards three species of the genus Clostridium such as C. perfringens , type A...

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Veröffentlicht in:Zentralblatt für Mikrobiologie 1992-01, Vol.147 (1-2), p.71-79
Hauptverfasser: Ciganekova, V, Kallova, J
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Sprache:eng
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Clostridium
Lactobacillus
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Kallova, J
description The study contains the results of determination of antibacteria of the newly synthesized series of N-(2-(dodecanoyl-methylamine)ethyl)-alkyldimethylammonium bromides. The efficiency of the compounds has been characterized towards three species of the genus Clostridium such as C. perfringens , type A, C. bifermentans, C. sporogenes and one strain of the genus Lactobacillus such as L. yamanashiensis . The antibacterial activity of the studied compounds has been tested in different time intervals. Out of seven investigated compounds, four compounds exerted the pronounced antibacterial activity on Clostridia (CMIC equals 0.0039-0.0078 mmol/litre) and three compounds influenced the growth of L. yamanashiensis (MIC equals 0.004-0.006 mmol/litre). The most effective compound was found to be n-octyl derivative. These compounds were more effective towards the tested Clostridia strains than the comparing standard disinfectant such as Ajatin.
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source Alma/SFX Local Collection
subjects Clostridium
Lactobacillus
title Antibacterial activity of N-(2-(dodecanoyl-methylamine)ethyl)-alkyldimethylammonium bromides
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