Corpus Callosum Atrophy in Patients with Hereditary Diffuse Leukoencephalopathy with Neuroaxonal Spheroids: An MRI-based Study

Objective Hereditary diffuse leukoencephalopathy with neuroaxonal spheroids (HDLS) is an adult-onset white matter disease that presents clinically with cognitive, mental and motor dysfunction. Several autopsy reports have indicated that the corpus callosum (CC), the largest bundle of white matter, i...

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Veröffentlicht in:	Internal Medicine 2014, Vol.53(1), pp.21-27
Hauptverfasser:	Kinoshita, Michiaki, Kondo, Yasufumi, Yoshida, Kunihiro, Fukushima, Kazuhiro, Hoshi, Ken-ichi, Ishizawa, Keisuke, Araki, Nobuo, Yazawa, Ikuru, Washimi, Yukihiko, Saitoh, Banyu, Kira, Jun-ichi, Ikeda, Shu-ichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Atrophy - pathology colony stimulating factor 1 receptor (CSF1R) Corpus Callosum - pathology corpus callosum atrophy (CCA) corpus callosum index (CCI) Female hereditary diffuse leukoencephalopathy with neuroaxonal spheroids (HDLS) Humans Leukoencephalopathies - diagnosis Leukoencephalopathies - epidemiology Magnetic Resonance Imaging - methods Male Middle Aged Nerve Fibers, Myelinated - pathology Retrospective Studies white matter lesions (WMLs)
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