Paraneoplastic Neurological Syndrome in a Patient with Squamous Cell Lung Cancer
A 78-year-old man presented with urinary retention and difficulty walking. Both legs showed muscle weakness, and he was experiencing lower body hypoesthesia. T2-weighted magnetic resonance imaging revealed lesions with high signal intensity and enhancement in the spinal cord and cerebrum. A cerebros...
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| Veröffentlicht in: | Internal Medicine 2013, Vol.52(17), pp.1967-1970 |
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| container_end_page | 1970 |
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| container_issue | 17 |
| container_start_page | 1967 |
| container_title | Internal Medicine |
| container_volume | 52 |
| creator | Mori, Hidenori Yamada, Osamu Ohno, Yasushi Kaito, Daizo Yanase, Komei Ito, Fumitaka Endo, Junki Morishita, Megumi Funaguchi, Norihiko Minatoguchi, Shinya |
| description | A 78-year-old man presented with urinary retention and difficulty walking. Both legs showed muscle weakness, and he was experiencing lower body hypoesthesia. T2-weighted magnetic resonance imaging revealed lesions with high signal intensity and enhancement in the spinal cord and cerebrum. A cerebrospinal fluid specimen showed inflammatory changes, but negative cytology findings. Chest computed tomography revealed a tumor measuring 40 mm in diameter, and a lung biopsy revealed the presence of squamous cell carcinoma. We diagnosed the patient with paraneoplastic neurological syndrome related to lung cancer. The patient was treated with steroid pulse therapy and chemotherapy, which relieved the symptoms and enabled the patient to achieve an independent gait. |
| doi_str_mv | 10.2169/internalmedicine.52.0442 |
| format | Article |
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The patient was treated with steroid pulse therapy and chemotherapy, which relieved the symptoms and enabled the patient to achieve an independent gait.</description><identifier>ISSN: 0918-2918</identifier><identifier>EISSN: 1349-7235</identifier><identifier>DOI: 10.2169/internalmedicine.52.0442</identifier><identifier>PMID: 23994993</identifier><language>eng</language><publisher>Japan: The Japanese Society of Internal Medicine</publisher><subject>Aged ; Carcinoma, Squamous Cell - complications ; Carcinoma, Squamous Cell - diagnosis ; encephalomyelitis ; Humans ; lung cancer ; Lung Neoplasms - complications ; Lung Neoplasms - diagnosis ; Male ; myelitis ; Nervous System Diseases - complications ; Nervous System Diseases - diagnosis ; paraneoplastic neurological syndrome ; Paraneoplastic Syndromes - complications ; Paraneoplastic Syndromes - diagnosis ; squamous cell carcinoma</subject><ispartof>Internal Medicine, 2013, Vol.52(17), pp.1967-1970</ispartof><rights>2013 by The Japanese Society of Internal Medicine</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c510t-44b71c711d889c2601ee51ad56c32149d59faa46d278c3e67150b8eed7d7a9363</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,1877,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23994993$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mori, Hidenori</creatorcontrib><creatorcontrib>Yamada, Osamu</creatorcontrib><creatorcontrib>Ohno, Yasushi</creatorcontrib><creatorcontrib>Kaito, Daizo</creatorcontrib><creatorcontrib>Yanase, Komei</creatorcontrib><creatorcontrib>Ito, Fumitaka</creatorcontrib><creatorcontrib>Endo, Junki</creatorcontrib><creatorcontrib>Morishita, Megumi</creatorcontrib><creatorcontrib>Funaguchi, Norihiko</creatorcontrib><creatorcontrib>Minatoguchi, Shinya</creatorcontrib><title>Paraneoplastic Neurological Syndrome in a Patient with Squamous Cell Lung Cancer</title><title>Internal Medicine</title><addtitle>Intern. 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The patient was treated with steroid pulse therapy and chemotherapy, which relieved the symptoms and enabled the patient to achieve an independent gait.</description><subject>Aged</subject><subject>Carcinoma, Squamous Cell - complications</subject><subject>Carcinoma, Squamous Cell - diagnosis</subject><subject>encephalomyelitis</subject><subject>Humans</subject><subject>lung cancer</subject><subject>Lung Neoplasms - complications</subject><subject>Lung Neoplasms - diagnosis</subject><subject>Male</subject><subject>myelitis</subject><subject>Nervous System Diseases - complications</subject><subject>Nervous System Diseases - diagnosis</subject><subject>paraneoplastic neurological syndrome</subject><subject>Paraneoplastic Syndromes - complications</subject><subject>Paraneoplastic Syndromes - diagnosis</subject><subject>squamous cell carcinoma</subject><issn>0918-2918</issn><issn>1349-7235</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtrGzEQgEVpaJy0f6Ho2Ms6eq0ex2LStGAaQ9qzGGvHjsKu1pF2Cf73WWPHh1LIZeYw37w-Qihnc8G1u4lpwJyg7bCJISac12LOlBIfyIxL5SojZP2RzJjjthJTuCRXpTwxJq1x4hO5FNI55ZyckdUKMiTsdy2UIQb6G8fct_02Bmjpwz41ue-QxkSBrmCImAb6EodH-vA8QtePhS6wbelyTFu6gBQwfyYXG2gLfjnla_L3x-2fxc9qeX_3a_F9WYWas6FSam14MJw31rogNOOINYem1kEKrlxTuw2A0o0wNkjUhtdsbREb0xhwUstr8u04d5f75xHL4LtYwnTM4ZuxeK6F0Jw5Kd5HlXBaKmPthNojGnJfSsaN3-XYQd57zvxBvf9Xva-FP6ifWr-etozrqXhufHM9AfdH4KkMsMUzAHkS3-J_J3NziKcVZzI8QvaY5CvFkqGF</recordid><startdate>20130101</startdate><enddate>20130101</enddate><creator>Mori, Hidenori</creator><creator>Yamada, Osamu</creator><creator>Ohno, Yasushi</creator><creator>Kaito, Daizo</creator><creator>Yanase, Komei</creator><creator>Ito, Fumitaka</creator><creator>Endo, Junki</creator><creator>Morishita, Megumi</creator><creator>Funaguchi, Norihiko</creator><creator>Minatoguchi, Shinya</creator><general>The Japanese Society of Internal Medicine</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7TK</scope></search><sort><creationdate>20130101</creationdate><title>Paraneoplastic Neurological Syndrome in a Patient with Squamous Cell Lung Cancer</title><author>Mori, Hidenori ; Yamada, Osamu ; Ohno, Yasushi ; Kaito, Daizo ; Yanase, Komei ; Ito, Fumitaka ; Endo, Junki ; Morishita, Megumi ; Funaguchi, Norihiko ; Minatoguchi, Shinya</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c510t-44b71c711d889c2601ee51ad56c32149d59faa46d278c3e67150b8eed7d7a9363</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Aged</topic><topic>Carcinoma, Squamous Cell - complications</topic><topic>Carcinoma, Squamous Cell - diagnosis</topic><topic>encephalomyelitis</topic><topic>Humans</topic><topic>lung cancer</topic><topic>Lung Neoplasms - complications</topic><topic>Lung Neoplasms - diagnosis</topic><topic>Male</topic><topic>myelitis</topic><topic>Nervous System Diseases - complications</topic><topic>Nervous System Diseases - diagnosis</topic><topic>paraneoplastic neurological syndrome</topic><topic>Paraneoplastic Syndromes - complications</topic><topic>Paraneoplastic Syndromes - diagnosis</topic><topic>squamous cell carcinoma</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mori, Hidenori</creatorcontrib><creatorcontrib>Yamada, Osamu</creatorcontrib><creatorcontrib>Ohno, Yasushi</creatorcontrib><creatorcontrib>Kaito, Daizo</creatorcontrib><creatorcontrib>Yanase, Komei</creatorcontrib><creatorcontrib>Ito, Fumitaka</creatorcontrib><creatorcontrib>Endo, Junki</creatorcontrib><creatorcontrib>Morishita, Megumi</creatorcontrib><creatorcontrib>Funaguchi, Norihiko</creatorcontrib><creatorcontrib>Minatoguchi, Shinya</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Neurosciences Abstracts</collection><jtitle>Internal Medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mori, Hidenori</au><au>Yamada, Osamu</au><au>Ohno, Yasushi</au><au>Kaito, Daizo</au><au>Yanase, Komei</au><au>Ito, Fumitaka</au><au>Endo, Junki</au><au>Morishita, Megumi</au><au>Funaguchi, Norihiko</au><au>Minatoguchi, Shinya</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Paraneoplastic Neurological Syndrome in a Patient with Squamous Cell Lung Cancer</atitle><jtitle>Internal Medicine</jtitle><addtitle>Intern. Med.</addtitle><date>2013-01-01</date><risdate>2013</risdate><volume>52</volume><issue>17</issue><spage>1967</spage><epage>1970</epage><pages>1967-1970</pages><issn>0918-2918</issn><eissn>1349-7235</eissn><abstract>A 78-year-old man presented with urinary retention and difficulty walking. Both legs showed muscle weakness, and he was experiencing lower body hypoesthesia. T2-weighted magnetic resonance imaging revealed lesions with high signal intensity and enhancement in the spinal cord and cerebrum. A cerebrospinal fluid specimen showed inflammatory changes, but negative cytology findings. Chest computed tomography revealed a tumor measuring 40 mm in diameter, and a lung biopsy revealed the presence of squamous cell carcinoma. We diagnosed the patient with paraneoplastic neurological syndrome related to lung cancer. The patient was treated with steroid pulse therapy and chemotherapy, which relieved the symptoms and enabled the patient to achieve an independent gait.</abstract><cop>Japan</cop><pub>The Japanese Society of Internal Medicine</pub><pmid>23994993</pmid><doi>10.2169/internalmedicine.52.0442</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0918-2918 |
| ispartof | Internal Medicine, 2013, Vol.52(17), pp.1967-1970 |
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| subjects | Aged Carcinoma, Squamous Cell - complications Carcinoma, Squamous Cell - diagnosis encephalomyelitis Humans lung cancer Lung Neoplasms - complications Lung Neoplasms - diagnosis Male myelitis Nervous System Diseases - complications Nervous System Diseases - diagnosis paraneoplastic neurological syndrome Paraneoplastic Syndromes - complications Paraneoplastic Syndromes - diagnosis squamous cell carcinoma |
| title | Paraneoplastic Neurological Syndrome in a Patient with Squamous Cell Lung Cancer |
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