Exposure method development for risk assessment to cosmetic products using a standard composition
•A method was established to assess qualitative and quantitative cosmetic product compositions.•It is applicable to all cosmetics and supplies concentration data for all ingredients.•Probabilistic exposure to nail polish composition was performed using the Monte Carlo technique.•This method allows a...
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| Veröffentlicht in: | Food and chemical toxicology 2014-06, Vol.68, p.108-116 |
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| container_title | Food and chemical toxicology |
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| creator | Chevillotte, G. Ficheux, A.S. Morisset, T. Roudot, A.C. |
| description | •A method was established to assess qualitative and quantitative cosmetic product compositions.•It is applicable to all cosmetics and supplies concentration data for all ingredients.•Probabilistic exposure to nail polish composition was performed using the Monte Carlo technique.•This method allows a global risk assessment for cosmetic products.
In a risk assessment of cosmetic products, it is necessary to know both qualitative and quantitative compositions. Currently, European Regulation No. 1223/2009 requires the industries to provide ingredient lists for finished cosmetic products but not their concentrations. Ingredient concentrations are available in few bibliographic references but in an incomplete and approximate way.
In this study, we propose a method to qualitatively and quantitatively estimate the composition of a cosmetic product. This method has the advantages of being applicable to all cosmetic products and supplying concentration data for all ingredients. The results obtained seem quite fair compared to literature data. Applied to nail polish as an example, this method can be used to assess exposure per ingredient according to the Monte Carlo probabilistic method. It should be promising to assess the consumer risk to cosmetic product compositions. |
| doi_str_mv | 10.1016/j.fct.2014.03.010 |
| format | Article |
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In a risk assessment of cosmetic products, it is necessary to know both qualitative and quantitative compositions. Currently, European Regulation No. 1223/2009 requires the industries to provide ingredient lists for finished cosmetic products but not their concentrations. Ingredient concentrations are available in few bibliographic references but in an incomplete and approximate way.
In this study, we propose a method to qualitatively and quantitatively estimate the composition of a cosmetic product. This method has the advantages of being applicable to all cosmetic products and supplying concentration data for all ingredients. The results obtained seem quite fair compared to literature data. Applied to nail polish as an example, this method can be used to assess exposure per ingredient according to the Monte Carlo probabilistic method. It should be promising to assess the consumer risk to cosmetic product compositions.</description><identifier>ISSN: 0278-6915</identifier><identifier>EISSN: 1873-6351</identifier><identifier>DOI: 10.1016/j.fct.2014.03.010</identifier><identifier>PMID: 24636944</identifier><identifier>CODEN: FCTOD7</identifier><language>eng</language><publisher>Oxford: Elsevier Ltd</publisher><subject>Adolescent ; Adult ; Aged ; Aged, 80 and over ; Biological and medical sciences ; Child ; Child, Preschool ; Composition ; Consumer Product Safety - standards ; Cosmetic products ; Cosmetics - toxicity ; Domestic and cosmetic products toxicology ; Exposure ; Female ; Food toxicology ; Humans ; Infant ; Infant, Newborn ; Medical sciences ; Middle Aged ; Nail polish ; Risk ; Risk Assessment ; Toxicity Tests - methods ; Toxicology ; Young Adult</subject><ispartof>Food and chemical toxicology, 2014-06, Vol.68, p.108-116</ispartof><rights>2014 Elsevier Ltd</rights><rights>2015 INIST-CNRS</rights><rights>Copyright © 2014 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c416t-da8ffad40198b3cab5097f580eea9dd723c691e03029511aa2e003fb51c1b87c3</citedby><cites>FETCH-LOGICAL-c416t-da8ffad40198b3cab5097f580eea9dd723c691e03029511aa2e003fb51c1b87c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.fct.2014.03.010$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3536,27903,27904,45974</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=28503078$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24636944$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chevillotte, G.</creatorcontrib><creatorcontrib>Ficheux, A.S.</creatorcontrib><creatorcontrib>Morisset, T.</creatorcontrib><creatorcontrib>Roudot, A.C.</creatorcontrib><title>Exposure method development for risk assessment to cosmetic products using a standard composition</title><title>Food and chemical toxicology</title><addtitle>Food Chem Toxicol</addtitle><description>•A method was established to assess qualitative and quantitative cosmetic product compositions.•It is applicable to all cosmetics and supplies concentration data for all ingredients.•Probabilistic exposure to nail polish composition was performed using the Monte Carlo technique.•This method allows a global risk assessment for cosmetic products.
In a risk assessment of cosmetic products, it is necessary to know both qualitative and quantitative compositions. Currently, European Regulation No. 1223/2009 requires the industries to provide ingredient lists for finished cosmetic products but not their concentrations. Ingredient concentrations are available in few bibliographic references but in an incomplete and approximate way.
In this study, we propose a method to qualitatively and quantitatively estimate the composition of a cosmetic product. This method has the advantages of being applicable to all cosmetic products and supplying concentration data for all ingredients. The results obtained seem quite fair compared to literature data. Applied to nail polish as an example, this method can be used to assess exposure per ingredient according to the Monte Carlo probabilistic method. It should be promising to assess the consumer risk to cosmetic product compositions.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Biological and medical sciences</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Composition</subject><subject>Consumer Product Safety - standards</subject><subject>Cosmetic products</subject><subject>Cosmetics - toxicity</subject><subject>Domestic and cosmetic products toxicology</subject><subject>Exposure</subject><subject>Female</subject><subject>Food toxicology</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Nail polish</subject><subject>Risk</subject><subject>Risk Assessment</subject><subject>Toxicity Tests - methods</subject><subject>Toxicology</subject><subject>Young Adult</subject><issn>0278-6915</issn><issn>1873-6351</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1v1DAQhi0EokvhB3BBviBxSZiJ8ylOqCofUqVe2rPl2BPwksSLx6nov8ftLnDjZMt65vU7jxCvEUoEbN_vy8mmsgKsS1AlIDwRO-w7VbSqwadiB1XXF-2AzZl4wbwHgA679rk4q-pWtUNd74S5_HUIvEWSC6XvwUlHdzSHw0JrklOIMnr-IQ0zMT--pSBtyNfkrTzE4DabWG7s12_SSE5mdSa6jCw51icf1pfi2WRmplen81zcfrq8ufhSXF1__nrx8aqwNbapcKafJuNqwKEflTVjA0M3NT0QmcG5rlI2b0KgoBoaRGMqAlDT2KDFse-sOhfvjrm51c-NOOnFs6V5NiuFjTW2VdVC3yBkFI-ojYE50qQP0S8m3msE_WBW73U2qx_MalAaHmfenOK3cSH3d-KPygy8PQGGrZmnaFbr-R_XN7l712fuw5GjLOPOU9RsPa2WnI-UP3XB_6fGb9Zpl-c</recordid><startdate>20140601</startdate><enddate>20140601</enddate><creator>Chevillotte, G.</creator><creator>Ficheux, A.S.</creator><creator>Morisset, T.</creator><creator>Roudot, A.C.</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T2</scope><scope>7U1</scope><scope>7U2</scope><scope>7U7</scope><scope>C1K</scope></search><sort><creationdate>20140601</creationdate><title>Exposure method development for risk assessment to cosmetic products using a standard composition</title><author>Chevillotte, G. ; Ficheux, A.S. ; Morisset, T. ; Roudot, A.C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c416t-da8ffad40198b3cab5097f580eea9dd723c691e03029511aa2e003fb51c1b87c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Biological and medical sciences</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Composition</topic><topic>Consumer Product Safety - standards</topic><topic>Cosmetic products</topic><topic>Cosmetics - toxicity</topic><topic>Domestic and cosmetic products toxicology</topic><topic>Exposure</topic><topic>Female</topic><topic>Food toxicology</topic><topic>Humans</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Nail polish</topic><topic>Risk</topic><topic>Risk Assessment</topic><topic>Toxicity Tests - methods</topic><topic>Toxicology</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chevillotte, G.</creatorcontrib><creatorcontrib>Ficheux, A.S.</creatorcontrib><creatorcontrib>Morisset, T.</creatorcontrib><creatorcontrib>Roudot, A.C.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Risk Abstracts</collection><collection>Safety Science and Risk</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><jtitle>Food and chemical toxicology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chevillotte, G.</au><au>Ficheux, A.S.</au><au>Morisset, T.</au><au>Roudot, A.C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Exposure method development for risk assessment to cosmetic products using a standard composition</atitle><jtitle>Food and chemical toxicology</jtitle><addtitle>Food Chem Toxicol</addtitle><date>2014-06-01</date><risdate>2014</risdate><volume>68</volume><spage>108</spage><epage>116</epage><pages>108-116</pages><issn>0278-6915</issn><eissn>1873-6351</eissn><coden>FCTOD7</coden><abstract>•A method was established to assess qualitative and quantitative cosmetic product compositions.•It is applicable to all cosmetics and supplies concentration data for all ingredients.•Probabilistic exposure to nail polish composition was performed using the Monte Carlo technique.•This method allows a global risk assessment for cosmetic products.
In a risk assessment of cosmetic products, it is necessary to know both qualitative and quantitative compositions. Currently, European Regulation No. 1223/2009 requires the industries to provide ingredient lists for finished cosmetic products but not their concentrations. Ingredient concentrations are available in few bibliographic references but in an incomplete and approximate way.
In this study, we propose a method to qualitatively and quantitatively estimate the composition of a cosmetic product. This method has the advantages of being applicable to all cosmetic products and supplying concentration data for all ingredients. The results obtained seem quite fair compared to literature data. Applied to nail polish as an example, this method can be used to assess exposure per ingredient according to the Monte Carlo probabilistic method. It should be promising to assess the consumer risk to cosmetic product compositions.</abstract><cop>Oxford</cop><pub>Elsevier Ltd</pub><pmid>24636944</pmid><doi>10.1016/j.fct.2014.03.010</doi><tpages>9</tpages></addata></record> |
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| identifier | ISSN: 0278-6915 |
| ispartof | Food and chemical toxicology, 2014-06, Vol.68, p.108-116 |
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| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adolescent Adult Aged Aged, 80 and over Biological and medical sciences Child Child, Preschool Composition Consumer Product Safety - standards Cosmetic products Cosmetics - toxicity Domestic and cosmetic products toxicology Exposure Female Food toxicology Humans Infant Infant, Newborn Medical sciences Middle Aged Nail polish Risk Risk Assessment Toxicity Tests - methods Toxicology Young Adult |
| title | Exposure method development for risk assessment to cosmetic products using a standard composition |
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