Octyl-cyanoacrylate skin adhesive is effective for wound closure in posterior spinal surgery without increased risk of wound complications
Abstract Objective Few published studies have examined the complication profile after posterior spinal surgery wherein absorbable, subcuticular suture and cyanoacrylate skin adhesives (CSA) were used for incision closure. The purpose of this report is to compare the rate and profile of wound complic...
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Veröffentlicht in: | Clinical neurology and neurosurgery 2014-10, Vol.125, p.137-142 |
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description | Abstract Objective Few published studies have examined the complication profile after posterior spinal surgery wherein absorbable, subcuticular suture and cyanoacrylate skin adhesives (CSA) were used for incision closure. The purpose of this report is to compare the rate and profile of wound complications in a large number of patients who underwent posterior spinal surgery with CSA skin closure to rates of similar complications with standard nylon closure techniques. Methods The prospective database of all surgical cases maintained by the senior author was retrospectively reviewed. Three hundred eighty-two patients underwent posterior spinal surgery for degenerative, oncologic and traumatic pathology. Wound-related complications, including cerebrospinal fluid leak, wound infection and dehiscence were analyzed in all patients. Results These data establish that the incisions in patients who undergo posterior spinal surgery can be safely and successfully closed with subcuticular Monocryl™ and CSA without increased risk of CSF leak, wound infection or dehiscence. Rates of these complications were similar between the study population, a small subset of patients treated with traditional closure techniques and those in the established literature. Conclusions CSA is a safe method to achieve ultimate skin closure in patients who undergo posterior spinal surgery without increased risk of wound-related complications, even in those patients undergoing intradural procedures. |
doi_str_mv | 10.1016/j.clineuro.2014.07.026 |
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The purpose of this report is to compare the rate and profile of wound complications in a large number of patients who underwent posterior spinal surgery with CSA skin closure to rates of similar complications with standard nylon closure techniques. Methods The prospective database of all surgical cases maintained by the senior author was retrospectively reviewed. Three hundred eighty-two patients underwent posterior spinal surgery for degenerative, oncologic and traumatic pathology. Wound-related complications, including cerebrospinal fluid leak, wound infection and dehiscence were analyzed in all patients. Results These data establish that the incisions in patients who undergo posterior spinal surgery can be safely and successfully closed with subcuticular Monocryl™ and CSA without increased risk of CSF leak, wound infection or dehiscence. Rates of these complications were similar between the study population, a small subset of patients treated with traditional closure techniques and those in the established literature. Conclusions CSA is a safe method to achieve ultimate skin closure in patients who undergo posterior spinal surgery without increased risk of wound-related complications, even in those patients undergoing intradural procedures.</description><identifier>ISSN: 0303-8467</identifier><identifier>EISSN: 1872-6968</identifier><identifier>DOI: 10.1016/j.clineuro.2014.07.026</identifier><identifier>PMID: 25128654</identifier><identifier>CODEN: CNNSBV</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Adolescent ; Adult ; Aged ; Aged, 80 and over ; Antibiotics ; Back surgery ; Cyanoacrylate skin adhesives ; Cyanoacrylates - therapeutic use ; Female ; Health Insurance Portability & Accountability Act 1996-US ; Humans ; Infections ; Male ; Middle Aged ; Neurology ; Neurosurgery ; Neurosurgical Procedures ; Pathology ; Polylactic acid ; Prospective Studies ; Radiation therapy ; Risk ; Risk factors ; Skin - drug effects ; Spine - surgery ; Surgery ; Surgical site infection ; Surgical Wound Infection - epidemiology ; Suture Techniques ; Tissue Adhesives - therapeutic use ; Wound closure ; Wound Closure Techniques ; Wound complication ; Wound healing ; Young Adult</subject><ispartof>Clinical neurology and neurosurgery, 2014-10, Vol.125, p.137-142</ispartof><rights>2014</rights><rights>Copyright © 2014. Published by Elsevier B.V.</rights><rights>Copyright Elsevier Limited 2014</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c509t-cfaaa3f5698404724b7dd2eff89555c8ac58bcaae8aecf57e61c865a7f96f2773</citedby><cites>FETCH-LOGICAL-c509t-cfaaa3f5698404724b7dd2eff89555c8ac58bcaae8aecf57e61c865a7f96f2773</cites><orcidid>0000-0001-8666-9706</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0303846714002868$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25128654$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Howard, Brian M</creatorcontrib><creatorcontrib>Eshraghi, Sheila R</creatorcontrib><creatorcontrib>Holland, Christopher M</creatorcontrib><creatorcontrib>Refai, Daniel</creatorcontrib><title>Octyl-cyanoacrylate skin adhesive is effective for wound closure in posterior spinal surgery without increased risk of wound complications</title><title>Clinical neurology and neurosurgery</title><addtitle>Clin Neurol Neurosurg</addtitle><description>Abstract Objective Few published studies have examined the complication profile after posterior spinal surgery wherein absorbable, subcuticular suture and cyanoacrylate skin adhesives (CSA) were used for incision closure. The purpose of this report is to compare the rate and profile of wound complications in a large number of patients who underwent posterior spinal surgery with CSA skin closure to rates of similar complications with standard nylon closure techniques. Methods The prospective database of all surgical cases maintained by the senior author was retrospectively reviewed. Three hundred eighty-two patients underwent posterior spinal surgery for degenerative, oncologic and traumatic pathology. Wound-related complications, including cerebrospinal fluid leak, wound infection and dehiscence were analyzed in all patients. Results These data establish that the incisions in patients who undergo posterior spinal surgery can be safely and successfully closed with subcuticular Monocryl™ and CSA without increased risk of CSF leak, wound infection or dehiscence. Rates of these complications were similar between the study population, a small subset of patients treated with traditional closure techniques and those in the established literature. Conclusions CSA is a safe method to achieve ultimate skin closure in patients who undergo posterior spinal surgery without increased risk of wound-related complications, even in those patients undergoing intradural procedures.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Antibiotics</subject><subject>Back surgery</subject><subject>Cyanoacrylate skin adhesives</subject><subject>Cyanoacrylates - therapeutic use</subject><subject>Female</subject><subject>Health Insurance Portability & Accountability Act 1996-US</subject><subject>Humans</subject><subject>Infections</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Neurology</subject><subject>Neurosurgery</subject><subject>Neurosurgical Procedures</subject><subject>Pathology</subject><subject>Polylactic acid</subject><subject>Prospective Studies</subject><subject>Radiation therapy</subject><subject>Risk</subject><subject>Risk factors</subject><subject>Skin - drug effects</subject><subject>Spine - surgery</subject><subject>Surgery</subject><subject>Surgical site infection</subject><subject>Surgical Wound Infection - epidemiology</subject><subject>Suture Techniques</subject><subject>Tissue Adhesives - therapeutic use</subject><subject>Wound closure</subject><subject>Wound Closure Techniques</subject><subject>Wound complication</subject><subject>Wound healing</subject><subject>Young Adult</subject><issn>0303-8467</issn><issn>1872-6968</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqNkk1v1DAQhi0EokvhL1SWuHBJ8Ef8kQsCVeVDqtQDcLa8zph6NxsHO2mVv8CvxtF2QeoFTtZonnk9M-8gdEFJTQmVb3e168MAc4o1I7SpiaoJk0_QhmrFKtlK_RRtCCe80o1UZ-hFzjtCCOdSP0dnTFCmpWg26NeNm5a-cosdonVp6e0EOO_DgG13CzncAQ4Zg_fgpjXwMeH7OA8ddn3McyrpAY8xT5BCSeUxDLbHJfED0oLvw3Qb56kwLoHN0OEU8h5Hf9KIh7EPzk4hDvkleuZtn-HVw3uOvn-8-nb5ubq--fTl8sN15QRpp8p5ay33Qra6IY1izVZ1HSsd6lYI4bR1Qm-dtaAtOC8USOrKrFb5VnqmFD9Hb466Y4o_Z8iTOYTsoO_tAHHOhkrGJBFM_AcqZMMFJ5oX9PUjdBfnVJaxCtKGtIrrVVAeKZdizgm8GVM42LQYSsxqrNmZk7FmNdYQZYqxpfDiQX7eHqD7U3ZysgDvjwCU1d0FSCa7AIODLqTineli-Pcf7x5JrFixp9_DAvnvPCYzQ8zX9bzW6yrTkdKE5r8BG5PQbQ</recordid><startdate>20141001</startdate><enddate>20141001</enddate><creator>Howard, Brian M</creator><creator>Eshraghi, Sheila R</creator><creator>Holland, Christopher M</creator><creator>Refai, Daniel</creator><general>Elsevier B.V</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>MBDVC</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-8666-9706</orcidid></search><sort><creationdate>20141001</creationdate><title>Octyl-cyanoacrylate skin adhesive is effective for wound closure in posterior spinal surgery without increased risk of wound complications</title><author>Howard, Brian M ; Eshraghi, Sheila R ; Holland, Christopher M ; Refai, Daniel</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c509t-cfaaa3f5698404724b7dd2eff89555c8ac58bcaae8aecf57e61c865a7f96f2773</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Antibiotics</topic><topic>Back surgery</topic><topic>Cyanoacrylate skin adhesives</topic><topic>Cyanoacrylates - therapeutic use</topic><topic>Female</topic><topic>Health Insurance Portability & Accountability Act 1996-US</topic><topic>Humans</topic><topic>Infections</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Neurology</topic><topic>Neurosurgery</topic><topic>Neurosurgical Procedures</topic><topic>Pathology</topic><topic>Polylactic acid</topic><topic>Prospective Studies</topic><topic>Radiation therapy</topic><topic>Risk</topic><topic>Risk factors</topic><topic>Skin - drug effects</topic><topic>Spine - surgery</topic><topic>Surgery</topic><topic>Surgical site infection</topic><topic>Surgical Wound Infection - epidemiology</topic><topic>Suture Techniques</topic><topic>Tissue Adhesives - therapeutic use</topic><topic>Wound closure</topic><topic>Wound Closure Techniques</topic><topic>Wound complication</topic><topic>Wound healing</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Howard, Brian M</creatorcontrib><creatorcontrib>Eshraghi, Sheila R</creatorcontrib><creatorcontrib>Holland, Christopher M</creatorcontrib><creatorcontrib>Refai, Daniel</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Neurosciences Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical neurology and neurosurgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Howard, Brian M</au><au>Eshraghi, Sheila R</au><au>Holland, Christopher M</au><au>Refai, Daniel</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Octyl-cyanoacrylate skin adhesive is effective for wound closure in posterior spinal surgery without increased risk of wound complications</atitle><jtitle>Clinical neurology and neurosurgery</jtitle><addtitle>Clin Neurol Neurosurg</addtitle><date>2014-10-01</date><risdate>2014</risdate><volume>125</volume><spage>137</spage><epage>142</epage><pages>137-142</pages><issn>0303-8467</issn><eissn>1872-6968</eissn><coden>CNNSBV</coden><abstract>Abstract Objective Few published studies have examined the complication profile after posterior spinal surgery wherein absorbable, subcuticular suture and cyanoacrylate skin adhesives (CSA) were used for incision closure. The purpose of this report is to compare the rate and profile of wound complications in a large number of patients who underwent posterior spinal surgery with CSA skin closure to rates of similar complications with standard nylon closure techniques. Methods The prospective database of all surgical cases maintained by the senior author was retrospectively reviewed. Three hundred eighty-two patients underwent posterior spinal surgery for degenerative, oncologic and traumatic pathology. Wound-related complications, including cerebrospinal fluid leak, wound infection and dehiscence were analyzed in all patients. Results These data establish that the incisions in patients who undergo posterior spinal surgery can be safely and successfully closed with subcuticular Monocryl™ and CSA without increased risk of CSF leak, wound infection or dehiscence. Rates of these complications were similar between the study population, a small subset of patients treated with traditional closure techniques and those in the established literature. Conclusions CSA is a safe method to achieve ultimate skin closure in patients who undergo posterior spinal surgery without increased risk of wound-related complications, even in those patients undergoing intradural procedures.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>25128654</pmid><doi>10.1016/j.clineuro.2014.07.026</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0001-8666-9706</orcidid></addata></record> |
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subjects | Adolescent Adult Aged Aged, 80 and over Antibiotics Back surgery Cyanoacrylate skin adhesives Cyanoacrylates - therapeutic use Female Health Insurance Portability & Accountability Act 1996-US Humans Infections Male Middle Aged Neurology Neurosurgery Neurosurgical Procedures Pathology Polylactic acid Prospective Studies Radiation therapy Risk Risk factors Skin - drug effects Spine - surgery Surgery Surgical site infection Surgical Wound Infection - epidemiology Suture Techniques Tissue Adhesives - therapeutic use Wound closure Wound Closure Techniques Wound complication Wound healing Young Adult |
title | Octyl-cyanoacrylate skin adhesive is effective for wound closure in posterior spinal surgery without increased risk of wound complications |
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