Nodal pathway genes are down-regulated in facial asymmetry

Facial asymmetry is a common comorbid condition in patients with jaw deformation malocclusion. Heritability of malocclusion is advancing rapidly, but very little is known regarding genetic contributions to asymmetry. This study identifies differences in expression of key asymmetry-producing genes th...

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Veröffentlicht in:	The Journal of craniofacial surgery 2014-11, Vol.25 (6), p.e548-e555
Hauptverfasser:	Nicot, Romain, Hottenstein, Molly, Raoul, Gwenael, Ferri, Joel, Horton, Michael, Tobias, John W, Barton, Elisabeth, Gelé, Patrick, Sciote, James J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Down-Regulation - genetics Facial Asymmetry - genetics Facial Asymmetry - pathology Female Homeobox Protein PITX2 Homeodomain Proteins - genetics Humans Intracellular Signaling Peptides and Proteins - genetics Left-Right Determination Factors - genetics Male Malocclusion - genetics Malocclusion - pathology Masseter Muscle - metabolism Masseter Muscle - pathology Membrane Proteins - genetics Nodal Protein - genetics Signal Transduction - genetics Transcription Factors - genetics
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