Susceptible period for the teratogenicity of di- n-butyltin dichloride in rats

Pregnant rats were given di- n-butyltin dichloride (DBT) by gastric intubation at a dose of 20 mg/kg on days 7–9, 10–12 or 13–15 of pregnancy or at a dose of 20 or 40 mg/kg on day 6,7,8 or 9 of pregnancy. While treatment with DBT on days 7–9 was significantly and high teratogenic, no evidence of ter...

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