The vicinal chloroalcohols 1,3-dichloro-2-propanol (DC2P), 3-chloro-1,2-propanediol (3CPD) and 2-chloro-1,3-propanediol (2CPD) are not genotoxic in vivo in the wing spot test of Drosophila melanogaster

In this study, the vicinal chloroalcohols 1,3-dichloro-2-propanol (DC2P), 3-chloro-1,2-propanediol (3CPD) and 2-chloro-1,3-propanediol (2CPD) were investigated for genotoxicity in the wing spot test of Drosophila. DC2P is an important starting material in many processes of synthesis in chemical indu...

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Veröffentlicht in:	Mutation research 1997-11, Vol.394 (1), p.59-68
Hauptverfasser:	Frei, Hansjörg, Würgler, Friedrich E
Format:	Artikel
Sprache:	eng
Schlagworte:	1,3-Dichloro-2-propanol 2-Chloro-1,3-propanediol 3-Chloro-1,2-propanediol alpha-Chlorohydrin - analogs & derivatives alpha-Chlorohydrin - pharmacokinetics alpha-Chlorohydrin - toxicity Animals Biotransformation Chlorinated hydrocarbon Chloropropanol Drosophila melanogaster Drosophila melanogaster - drug effects Genotoxicity testing in vivo Glycerol chlorohydrin Mutagens - pharmacokinetics Mutagens - toxicity Somatic mutation and recombination test Vicinal chloroalcohol Wings, Animal - drug effects
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