Effect of Lung Squamous Cell Carcinoma Tumor Microenvironment on the CD105+ Endothelial Cell Proteome

In lung cancer, antiangiogenic treatment targeting tumor endothelial cells (ECs) provides a survival advantage. To fully elucidate the behavior of ECs in a tumor microenvironment, high-purity (>98%) normal, paratumor-, and tumor-derived CD105+ ECs were purified from lung squamous cell carcinoma b...

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Veröffentlicht in:	Journal of proteome research 2014-11, Vol.13 (11), p.4717-4729
Hauptverfasser:	Zhuo, Huiqin, Lyu, Zhi, Su, Jing, He, Jian, Pei, Yihua, Cheng, Xiao, Zhou, Nuo, Lu, Xiaoling, Zhou, Sufang, Zhao, Yongxiang
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, CD - metabolism Carcinoma, Squamous Cell - genetics Carcinoma, Squamous Cell - metabolism Chromatography, Ion Exchange Chromatography, Liquid Computational Biology Endoglin Endothelial Cells - metabolism Flow Cytometry Fluorescent Antibody Technique Gene Expression Regulation, Neoplastic - genetics Gene Expression Regulation, Neoplastic - physiology Humans Immunohistochemistry Isotope Labeling Lung Neoplasms - genetics Lung Neoplasms - metabolism Proteome - metabolism Real-Time Polymerase Chain Reaction Receptors, Cell Surface - metabolism Reverse Transcriptase Polymerase Chain Reaction Tandem Mass Spectrometry Tumor Microenvironment - physiology
Online-Zugang:	Volltext
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