Recipient Uridine 5′-Diphospho-glucuronosyltransferase UGT1A9 c.98T>C Variant Determines Transplanted Kidney Filtration Rate

Abstract Mycophenolic acid preparations are commonly used in prophylaxis of kidney allograft acute rejection. The medication is metabolized by uridine diphosphate glucuronosyltransferases, mainly UGT1A9 present in liver, kidney, and intestine. The effect of UGT1A9 allelic variants on drug metabolism...

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Veröffentlicht in:	Transplantation proceedings 2014-10, Vol.46 (8), p.2678-2682
Hauptverfasser:	Pazik, J, Ołdak, M, Lewandowski, Z, Dąbrowski, M, Podgórska, M, Sitarek, E, Malejczyk, J, Płoski, R, Durlik, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Delayed Graft Function - genetics Female Follow-Up Studies Genetic Markers Genotype Genotyping Techniques Glomerular Filtration Rate - genetics Glucuronosyltransferase - genetics Graft Rejection - genetics Graft Survival - genetics Humans Kidney Transplantation Male Middle Aged Polymorphism, Single Nucleotide Surgery Transplantation, Homologous
Online-Zugang:	Volltext
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