Induction of epidermal ornithine decarboxylase activity in mouse skin exposed to biogenic silica fibers

The present study demonstrates that biogenic silica fibers (BSF), previously shown to promote skin tumors in mice and more recently to promote the induction of mesotheliomas when injected into the pleural cavity of rats, rapidly induces epidermal ornithine decarboxylase (ODC) activity in SENCAR mice...

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Veröffentlicht in:	Carcinogenesis (New York) 1992-04, Vol.13 (4), p.617-620
Hauptverfasser:	Bhatt, Tarlochan S., Beltran, Linda M., Walker, Susan E., DiGiovanni, John
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Carcinogenesis, carcinogens and anticarcinogens Chemical agents Enzyme Induction - drug effects Female Hyperplasia Medical sciences Mice Ornithine Decarboxylase - biosynthesis Silicon Dioxide - adverse effects Skin - drug effects Skin - enzymology Skin - pathology Tetradecanoylphorbol Acetate Tumors
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