Stitching proteins into membranes, not sew simple

Most integral membrane proteins located within the endomembrane system of eukaryotic cells are first assembled co-translationally into the endoplasmic reticulum (ER) before being sorted and trafficked to other organelles. The assembly of membrane proteins is mediated by the ER translocon, which allo...

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Veröffentlicht in:	Biological chemistry 2014-12, Vol.395 (12), p.1417-1424
Hauptverfasser:	Whitley, Paul, Mingarro, Ismael
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals co-translational Endoplasmic Reticulum - metabolism Humans hydrophobic integration Intracellular Membranes - metabolism Membrane Proteins - analysis Membrane Proteins - metabolism Protein Structure, Tertiary Protein Transport translocation translocon transmembrane
Online-Zugang:	Volltext
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