Moisturizing effect of stable cream containing Crocus sativus extracts
The present study is about to prepare stable cream of water-in-oil emulsion containing extracts of Crocus sativus against its base (without extracts) taken as control, to determine its stability on different storage conditions and effects on skin moisture contents and transepidermal water loss. The...
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| Veröffentlicht in: | Pakistan journal of pharmaceutical sciences 2014-11, Vol.27 (6), p.1881-1884 |
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| container_issue | 6 |
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| container_title | Pakistan journal of pharmaceutical sciences |
| container_volume | 27 |
| creator | Akhtar, Naveed Khan, Haji Muhammad-Shoaib Ashraf, Shoaib Mohammad, Imran Shair Saqib, Najam-us Bashir, Kamran |
| description | The present study is about to prepare stable cream of water-in-oil emulsion containing extracts of Crocus sativus against its base (without extracts) taken as control, to determine its stability on different storage conditions and effects on skin moisture contents and transepidermal water loss. The formulation contains 3% Crocus sativus (Saffron) concentrated extracts, and the base containing no extract, were formulated. Different stability tests were done on samples, which placed at 8°C, 25°C, 40°C and 40°C with 75% relative humidity, for 4 week period. These formulations (Creams) were applied on the cheeks of human volunteers for 8week period. To evaluate any effect produced by these formulations different skin parameters were monitored every week. The significant results of this study explored the fact that water-in-oil emulsion topical cream of saffron formulated from Crocus sativus extract has absolute physical stability at different storage conditions. The increase in skin moisture contents and changes in transepidermal water loss were significant (p |
| format | Article |
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The formulation contains 3% Crocus sativus (Saffron) concentrated extracts, and the base containing no extract, were formulated. Different stability tests were done on samples, which placed at 8°C, 25°C, 40°C and 40°C with 75% relative humidity, for 4 week period. These formulations (Creams) were applied on the cheeks of human volunteers for 8week period. To evaluate any effect produced by these formulations different skin parameters were monitored every week. The significant results of this study explored the fact that water-in-oil emulsion topical cream of saffron formulated from Crocus sativus extract has absolute physical stability at different storage conditions. The increase in skin moisture contents and changes in transepidermal water loss were significant (p<0.05) with respect to base and formulation respectively. Topical cream of Crocus sativus showed significant moisturizing effects on human skin.</description><identifier>ISSN: 1011-601X</identifier><identifier>PMID: 25362612</identifier><language>eng</language><publisher>Pakistan: Pakistan Journal of Pharmaceutical Sciences</publisher><subject>Body Water - metabolism ; Crocus ; Emollients - pharmacology ; Emulsions ; Health aspects ; Humans ; Hydrogen-Ion Concentration ; Ointments ; Plant Extracts - pharmacology ; Saffron crocus ; Skin - drug effects ; Skin - metabolism ; Skin care</subject><ispartof>Pakistan journal of pharmaceutical sciences, 2014-11, Vol.27 (6), p.1881-1884</ispartof><rights>COPYRIGHT 2014 Pakistan Journal of Pharmaceutical Sciences</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25362612$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Akhtar, Naveed</creatorcontrib><creatorcontrib>Khan, Haji Muhammad-Shoaib</creatorcontrib><creatorcontrib>Ashraf, Shoaib</creatorcontrib><creatorcontrib>Mohammad, Imran Shair</creatorcontrib><creatorcontrib>Saqib, Najam-us</creatorcontrib><creatorcontrib>Bashir, Kamran</creatorcontrib><title>Moisturizing effect of stable cream containing Crocus sativus extracts</title><title>Pakistan journal of pharmaceutical sciences</title><addtitle>Pak J Pharm Sci</addtitle><description>The present study is about to prepare stable cream of water-in-oil emulsion containing extracts of Crocus sativus against its base (without extracts) taken as control, to determine its stability on different storage conditions and effects on skin moisture contents and transepidermal water loss. The formulation contains 3% Crocus sativus (Saffron) concentrated extracts, and the base containing no extract, were formulated. Different stability tests were done on samples, which placed at 8°C, 25°C, 40°C and 40°C with 75% relative humidity, for 4 week period. These formulations (Creams) were applied on the cheeks of human volunteers for 8week period. To evaluate any effect produced by these formulations different skin parameters were monitored every week. The significant results of this study explored the fact that water-in-oil emulsion topical cream of saffron formulated from Crocus sativus extract has absolute physical stability at different storage conditions. The increase in skin moisture contents and changes in transepidermal water loss were significant (p<0.05) with respect to base and formulation respectively. Topical cream of Crocus sativus showed significant moisturizing effects on human skin.</description><subject>Body Water - metabolism</subject><subject>Crocus</subject><subject>Emollients - pharmacology</subject><subject>Emulsions</subject><subject>Health aspects</subject><subject>Humans</subject><subject>Hydrogen-Ion Concentration</subject><subject>Ointments</subject><subject>Plant Extracts - pharmacology</subject><subject>Saffron crocus</subject><subject>Skin - drug effects</subject><subject>Skin - metabolism</subject><subject>Skin care</subject><issn>1011-601X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkEFLAzEQhXNQbK3-BVnw4mUlmaTZzbEUa4WKFwVvSzadlMjupiZZUX-9u7QeBJnDg-Gbx3tzQqaMMpZLyl4n5DzGN0qlUEqdkQnMuQTJYEpWj97F1Af37bpdhtaiSZm3WUy6bjAzAXWbGd8l7bqRWAZv-phFndzHoPiZgjYpXpBTq5uIl0edkZfV3fNynW-e7h-Wi02-g6JMeWkViFqg4KWSqtSq1hSoKJixyIxStLBczI2hAJqBlbXdaoZzAVIWjAHyGbk5-O6Df-8xpqp10WDT6A59HysmgVLglMGAXh_QnW6wcp31Y9QRrxZcSU6pEHygbv-hhtli64beaN2w_3NwdUzQ1y1uq31wrQ5f1e9L-Q9XJW9v</recordid><startdate>201411</startdate><enddate>201411</enddate><creator>Akhtar, Naveed</creator><creator>Khan, Haji Muhammad-Shoaib</creator><creator>Ashraf, Shoaib</creator><creator>Mohammad, Imran Shair</creator><creator>Saqib, Najam-us</creator><creator>Bashir, Kamran</creator><general>Pakistan Journal of Pharmaceutical Sciences</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>201411</creationdate><title>Moisturizing effect of stable cream containing Crocus sativus extracts</title><author>Akhtar, Naveed ; Khan, Haji Muhammad-Shoaib ; Ashraf, Shoaib ; Mohammad, Imran Shair ; Saqib, Najam-us ; Bashir, Kamran</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-g278t-8f924b4e4389698a9ba020471cfe1c9907f345cc022a12f6bfda1e542667112e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Body Water - metabolism</topic><topic>Crocus</topic><topic>Emollients - pharmacology</topic><topic>Emulsions</topic><topic>Health aspects</topic><topic>Humans</topic><topic>Hydrogen-Ion Concentration</topic><topic>Ointments</topic><topic>Plant Extracts - pharmacology</topic><topic>Saffron crocus</topic><topic>Skin - drug effects</topic><topic>Skin - metabolism</topic><topic>Skin care</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Akhtar, Naveed</creatorcontrib><creatorcontrib>Khan, Haji Muhammad-Shoaib</creatorcontrib><creatorcontrib>Ashraf, Shoaib</creatorcontrib><creatorcontrib>Mohammad, Imran Shair</creatorcontrib><creatorcontrib>Saqib, Najam-us</creatorcontrib><creatorcontrib>Bashir, Kamran</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Pakistan journal of pharmaceutical sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Akhtar, Naveed</au><au>Khan, Haji Muhammad-Shoaib</au><au>Ashraf, Shoaib</au><au>Mohammad, Imran Shair</au><au>Saqib, Najam-us</au><au>Bashir, Kamran</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Moisturizing effect of stable cream containing Crocus sativus extracts</atitle><jtitle>Pakistan journal of pharmaceutical sciences</jtitle><addtitle>Pak J Pharm Sci</addtitle><date>2014-11</date><risdate>2014</risdate><volume>27</volume><issue>6</issue><spage>1881</spage><epage>1884</epage><pages>1881-1884</pages><issn>1011-601X</issn><abstract>The present study is about to prepare stable cream of water-in-oil emulsion containing extracts of Crocus sativus against its base (without extracts) taken as control, to determine its stability on different storage conditions and effects on skin moisture contents and transepidermal water loss. The formulation contains 3% Crocus sativus (Saffron) concentrated extracts, and the base containing no extract, were formulated. Different stability tests were done on samples, which placed at 8°C, 25°C, 40°C and 40°C with 75% relative humidity, for 4 week period. These formulations (Creams) were applied on the cheeks of human volunteers for 8week period. To evaluate any effect produced by these formulations different skin parameters were monitored every week. The significant results of this study explored the fact that water-in-oil emulsion topical cream of saffron formulated from Crocus sativus extract has absolute physical stability at different storage conditions. The increase in skin moisture contents and changes in transepidermal water loss were significant (p<0.05) with respect to base and formulation respectively. Topical cream of Crocus sativus showed significant moisturizing effects on human skin.</abstract><cop>Pakistan</cop><pub>Pakistan Journal of Pharmaceutical Sciences</pub><pmid>25362612</pmid><tpages>4</tpages></addata></record> |
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| identifier | ISSN: 1011-601X |
| ispartof | Pakistan journal of pharmaceutical sciences, 2014-11, Vol.27 (6), p.1881-1884 |
| issn | 1011-601X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1620023012 |
| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Body Water - metabolism Crocus Emollients - pharmacology Emulsions Health aspects Humans Hydrogen-Ion Concentration Ointments Plant Extracts - pharmacology Saffron crocus Skin - drug effects Skin - metabolism Skin care |
| title | Moisturizing effect of stable cream containing Crocus sativus extracts |
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