Indium inhibits gap junctional communication between rat hepatocytes in primary culture

The effect of indium on gap junctional communication was investigated in primary cultured rat hepatocytes. Treatment of hepatocytes with indium chloride at concentrations of 100 μM to 1 mM for 2 h resulted in dose-dependent inhibition of gap junctional communication between hepatocytes. The effect o...

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Veröffentlicht in:	Toxicology letters 1992, Vol.60 (1), p.99-106
Hauptverfasser:	Xinbiao, Guo, Yasuo, Ohno, Toru, Kawanishi, Momoko, Sunouchi, Akira, Takanaka
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cell Communication - drug effects Cells, Cultured Chemical and industrial products toxicology. Toxic occupational diseases Dose-Response Relationship, Drug Gap junction Hepatocyte Indium Indium - pharmacology L-Lactate Dehydrogenase - metabolism Liver - drug effects Liver - ultrastructure Male Medical sciences Metals and various inorganic compounds Primary culture Rats Rats, Inbred Strains Tetrazolium Salts - metabolism Thiazoles - metabolism Toxicology
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