Cellular pharmacokinetics of carboplatin and cisplatin in relation to their cytotoxic action

We have studied the cellular pharmacokinetics of carboplatin (CBDCA), as part of the evaluation of the antitumor activity of CBDCA in cancers limited to the peritoneal cavity in comparison with cisplatin (cDDP). The uptake of CBDCA into L1210 (lymphosarcoma), CC531 (colonic carcinoma), COV413.B (hum...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biochemical pharmacology 1991-07, Vol.42 (2), p.357-363
Hauptverfasser:	Los, Gerrit, Verdegaal, Els, Noteborn, Hub P.J.M., Ruevekamp, Marjan, de Graeff, Alexander, Meesters, Eelco W., Ten Bokkel Huinink, Daan, McVie, J.Gordon
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic agents Biological and medical sciences Carboplatin - pharmacology Cell Line - metabolism Cell Survival - drug effects Cisplatin - pharmacology Colony-Forming Units Assay DNA - metabolism General aspects Humans Medical sciences Pharmacology. Drug treatments Platinum - analysis Spectrophotometry, Atomic Thymidine - metabolism Tumor Cells, Cultured - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!