Screening for the FIG-ROS1 fusion in biliary tract carcinomas by nested PCR

ROS1 rearrangements have been detected in a variety of tumors and are considered as suitable targets of anticancer therapies. We developed a new, quick, specific, and sensitive PCR test to screen for the FIG‐ROS1 fusion and applied it to a series of Italian patients with bile duct carcinoma (BTC). F...

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Veröffentlicht in:	Genes chromosomes & cancer 2014-12, Vol.53 (12), p.1033-1040
Hauptverfasser:	Peraldo Neia, Caterina, Cavalloni, Giuliana, Balsamo, Antonella, Venesio, Tiziana, Napoli, Francesca, Sassi, Francesco, Martin, Vittoria, Frattini, Milo, Aglietta, Massimo, Leone, Francesco
Format:	Artikel
Sprache:	eng
Schlagworte:	Bile Duct Neoplasms - genetics Bile Duct Neoplasms - pathology Carcinoma - pathology Cell Line, Tumor Humans Oncogene Proteins, Fusion - genetics Polymerase Chain Reaction Sensitivity and Specificity
Online-Zugang:	Volltext
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