A comparative study on enteric parasitic infections in immunocompetent and immunosuppressed children in Egypt
Diarrheal diseases are widespread all over the world, not only threaten human health but also greatly affect society and economy. Immune status may affect parasitic infections and the ability to combat such diseases. We aimed to investigate the prevalence of parasitic infections in immunosuppressed...
Gespeichert in:
| Veröffentlicht in: | Comparative clinical pathology 2014-09, Vol.23 (5), p.1509-1514 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1514 |
|---|---|
| container_issue | 5 |
| container_start_page | 1509 |
| container_title | Comparative clinical pathology |
| container_volume | 23 |
| creator | El-Mahallawy, Hadir El Basha, Noussa R. Zaki, Mayssa M. El-Arousy, Maha Elswaifi, Shaadi F. Abo-hashem, E. M. |
| description | Diarrheal diseases are widespread all over the world, not only threaten human health but also greatly affect society and economy. Immune status may affect parasitic infections and the ability to combat such diseases. We aimed to investigate the prevalence of parasitic infections in immunosuppressed pediatric patients in comparison to immunocompetent ones with gastroenteritis. A total of 189 stool samples were collected from 100 immunocompetent diarrheic children at Cairo University Children's Hospitals and 89 children with cancer and diarrhea at the National Cancer Institute (NCI), Cairo University. All cases were subjected to history taking and clinical examination. Stool samples were examined microscopically and by ELISA for
Entamoeba histolytica
,
Giardia lamblia
, and
Cryptosporidium
oocyts. Frequency and duration of both diarrhea and vomiting were significantly higher in immunosuppressed children (
P
|
| doi_str_mv | 10.1007/s00580-013-1814-5 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1618150575</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1618150575</sourcerecordid><originalsourceid>FETCH-LOGICAL-c2645-a7f1daa1e9d7b7fa1e92b89e57d43e1d4297c3359c36a37f764c915a0c5bc88c3</originalsourceid><addsrcrecordid>eNp1kU9LxDAQxYsouK5-AG8FL16qmaZJ2uOyrH9gwYuCt5BNpmuWbVqTVthvb0oXEcHTPCa_9xjykuQayB0QIu4DIawkGQGaQQlFxk6SGXAoM8bZ--mPLuA8uQhhRwiwktJZ0ixS3Tad8qq3X5iGfjCHtHUpuh691en4EmwflXU16t62LkSZ2qYZXDtasY9sqpw57sLQdR5DQJPqD7s3Ht1oWG0PXX-ZnNVqH_DqOOfJ28PqdfmUrV8en5eLdaZzXrBMiRqMUoCVERtRjyLflBUyYQqKYIq8EppSVmnKFRW14IWugCmi2UaXpabz5HbK7Xz7OWDoZWODxv1eOWyHIMffAEaYYBG9-YPu2sG7eJ0EximvOCurSMFEad-G4LGWnbeN8gcJRI4FyKkAGQuQYwFyTM4nT4is26L_lfyv6Rso6Ypr</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1563696589</pqid></control><display><type>article</type><title>A comparative study on enteric parasitic infections in immunocompetent and immunosuppressed children in Egypt</title><source>Springer Nature - Complete Springer Journals</source><creator>El-Mahallawy, Hadir ; El Basha, Noussa R. ; Zaki, Mayssa M. ; El-Arousy, Maha ; Elswaifi, Shaadi F. ; Abo-hashem, E. M.</creator><creatorcontrib>El-Mahallawy, Hadir ; El Basha, Noussa R. ; Zaki, Mayssa M. ; El-Arousy, Maha ; Elswaifi, Shaadi F. ; Abo-hashem, E. M.</creatorcontrib><description>Diarrheal diseases are widespread all over the world, not only threaten human health but also greatly affect society and economy. Immune status may affect parasitic infections and the ability to combat such diseases. We aimed to investigate the prevalence of parasitic infections in immunosuppressed pediatric patients in comparison to immunocompetent ones with gastroenteritis. A total of 189 stool samples were collected from 100 immunocompetent diarrheic children at Cairo University Children's Hospitals and 89 children with cancer and diarrhea at the National Cancer Institute (NCI), Cairo University. All cases were subjected to history taking and clinical examination. Stool samples were examined microscopically and by ELISA for
Entamoeba histolytica
,
Giardia lamblia
, and
Cryptosporidium
oocyts. Frequency and duration of both diarrhea and vomiting were significantly higher in immunosuppressed children (
P
< 0.01).
E. histolytica
,
Giardia,
and
Cryptosporidium
were detected in 2 (1.1 %), 29 (15.3 %), and in 9 (4.8 %) samples, respectively, whereas 46 (24.3 %) cases were positive for other parasitic infections. Overall parasitic infections were positive in 86 stool samples (45.5 %): 41 belonging to immunocompetent patients (41 %) and 45 (50.6 %) to the immunosuppressed group though with no statistically important difference. Parasitic infections in Egyptian children with gastroenteritis are still high. No difference in prevalence of infections between immunosuppressed and immunocompetent children, yet clinical data were statistically higher in immunosuppressed patients (
P
< 0.01). ELISA is as good as microscopy and is advantageous in its ability to differentiate between
E
.
histolytica
and
Entamoeba dispar
, thus can aid routine labs in detecting parasitic pathogens.</description><identifier>ISSN: 1618-5641</identifier><identifier>EISSN: 1618-565X</identifier><identifier>DOI: 10.1007/s00580-013-1814-5</identifier><language>eng</language><publisher>London: Springer London</publisher><subject>Cryptosporidium ; Entamoeba dispar ; Entamoeba histolytica ; Giardia lamblia ; Hematology ; Medicine ; Medicine & Public Health ; Oncology ; Original Article ; Pathology</subject><ispartof>Comparative clinical pathology, 2014-09, Vol.23 (5), p.1509-1514</ispartof><rights>Springer-Verlag London 2013</rights><rights>Springer-Verlag London 2014</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2645-a7f1daa1e9d7b7fa1e92b89e57d43e1d4297c3359c36a37f764c915a0c5bc88c3</citedby><cites>FETCH-LOGICAL-c2645-a7f1daa1e9d7b7fa1e92b89e57d43e1d4297c3359c36a37f764c915a0c5bc88c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00580-013-1814-5$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00580-013-1814-5$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27903,27904,41467,42536,51298</link.rule.ids></links><search><creatorcontrib>El-Mahallawy, Hadir</creatorcontrib><creatorcontrib>El Basha, Noussa R.</creatorcontrib><creatorcontrib>Zaki, Mayssa M.</creatorcontrib><creatorcontrib>El-Arousy, Maha</creatorcontrib><creatorcontrib>Elswaifi, Shaadi F.</creatorcontrib><creatorcontrib>Abo-hashem, E. M.</creatorcontrib><title>A comparative study on enteric parasitic infections in immunocompetent and immunosuppressed children in Egypt</title><title>Comparative clinical pathology</title><addtitle>Comp Clin Pathol</addtitle><description>Diarrheal diseases are widespread all over the world, not only threaten human health but also greatly affect society and economy. Immune status may affect parasitic infections and the ability to combat such diseases. We aimed to investigate the prevalence of parasitic infections in immunosuppressed pediatric patients in comparison to immunocompetent ones with gastroenteritis. A total of 189 stool samples were collected from 100 immunocompetent diarrheic children at Cairo University Children's Hospitals and 89 children with cancer and diarrhea at the National Cancer Institute (NCI), Cairo University. All cases were subjected to history taking and clinical examination. Stool samples were examined microscopically and by ELISA for
Entamoeba histolytica
,
Giardia lamblia
, and
Cryptosporidium
oocyts. Frequency and duration of both diarrhea and vomiting were significantly higher in immunosuppressed children (
P
< 0.01).
E. histolytica
,
Giardia,
and
Cryptosporidium
were detected in 2 (1.1 %), 29 (15.3 %), and in 9 (4.8 %) samples, respectively, whereas 46 (24.3 %) cases were positive for other parasitic infections. Overall parasitic infections were positive in 86 stool samples (45.5 %): 41 belonging to immunocompetent patients (41 %) and 45 (50.6 %) to the immunosuppressed group though with no statistically important difference. Parasitic infections in Egyptian children with gastroenteritis are still high. No difference in prevalence of infections between immunosuppressed and immunocompetent children, yet clinical data were statistically higher in immunosuppressed patients (
P
< 0.01). ELISA is as good as microscopy and is advantageous in its ability to differentiate between
E
.
histolytica
and
Entamoeba dispar
, thus can aid routine labs in detecting parasitic pathogens.</description><subject>Cryptosporidium</subject><subject>Entamoeba dispar</subject><subject>Entamoeba histolytica</subject><subject>Giardia lamblia</subject><subject>Hematology</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Oncology</subject><subject>Original Article</subject><subject>Pathology</subject><issn>1618-5641</issn><issn>1618-565X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp1kU9LxDAQxYsouK5-AG8FL16qmaZJ2uOyrH9gwYuCt5BNpmuWbVqTVthvb0oXEcHTPCa_9xjykuQayB0QIu4DIawkGQGaQQlFxk6SGXAoM8bZ--mPLuA8uQhhRwiwktJZ0ixS3Tad8qq3X5iGfjCHtHUpuh691en4EmwflXU16t62LkSZ2qYZXDtasY9sqpw57sLQdR5DQJPqD7s3Ht1oWG0PXX-ZnNVqH_DqOOfJ28PqdfmUrV8en5eLdaZzXrBMiRqMUoCVERtRjyLflBUyYQqKYIq8EppSVmnKFRW14IWugCmi2UaXpabz5HbK7Xz7OWDoZWODxv1eOWyHIMffAEaYYBG9-YPu2sG7eJ0EximvOCurSMFEad-G4LGWnbeN8gcJRI4FyKkAGQuQYwFyTM4nT4is26L_lfyv6Rso6Ypr</recordid><startdate>20140901</startdate><enddate>20140901</enddate><creator>El-Mahallawy, Hadir</creator><creator>El Basha, Noussa R.</creator><creator>Zaki, Mayssa M.</creator><creator>El-Arousy, Maha</creator><creator>Elswaifi, Shaadi F.</creator><creator>Abo-hashem, E. M.</creator><general>Springer London</general><general>Springer Nature B.V</general><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7T5</scope><scope>7X7</scope><scope>7XB</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope></search><sort><creationdate>20140901</creationdate><title>A comparative study on enteric parasitic infections in immunocompetent and immunosuppressed children in Egypt</title><author>El-Mahallawy, Hadir ; El Basha, Noussa R. ; Zaki, Mayssa M. ; El-Arousy, Maha ; Elswaifi, Shaadi F. ; Abo-hashem, E. M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2645-a7f1daa1e9d7b7fa1e92b89e57d43e1d4297c3359c36a37f764c915a0c5bc88c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Cryptosporidium</topic><topic>Entamoeba dispar</topic><topic>Entamoeba histolytica</topic><topic>Giardia lamblia</topic><topic>Hematology</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Oncology</topic><topic>Original Article</topic><topic>Pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>El-Mahallawy, Hadir</creatorcontrib><creatorcontrib>El Basha, Noussa R.</creatorcontrib><creatorcontrib>Zaki, Mayssa M.</creatorcontrib><creatorcontrib>El-Arousy, Maha</creatorcontrib><creatorcontrib>Elswaifi, Shaadi F.</creatorcontrib><creatorcontrib>Abo-hashem, E. M.</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Proquest Nursing & Allied Health Source</collection><collection>Immunology Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Biological Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><jtitle>Comparative clinical pathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>El-Mahallawy, Hadir</au><au>El Basha, Noussa R.</au><au>Zaki, Mayssa M.</au><au>El-Arousy, Maha</au><au>Elswaifi, Shaadi F.</au><au>Abo-hashem, E. M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A comparative study on enteric parasitic infections in immunocompetent and immunosuppressed children in Egypt</atitle><jtitle>Comparative clinical pathology</jtitle><stitle>Comp Clin Pathol</stitle><date>2014-09-01</date><risdate>2014</risdate><volume>23</volume><issue>5</issue><spage>1509</spage><epage>1514</epage><pages>1509-1514</pages><issn>1618-5641</issn><eissn>1618-565X</eissn><abstract>Diarrheal diseases are widespread all over the world, not only threaten human health but also greatly affect society and economy. Immune status may affect parasitic infections and the ability to combat such diseases. We aimed to investigate the prevalence of parasitic infections in immunosuppressed pediatric patients in comparison to immunocompetent ones with gastroenteritis. A total of 189 stool samples were collected from 100 immunocompetent diarrheic children at Cairo University Children's Hospitals and 89 children with cancer and diarrhea at the National Cancer Institute (NCI), Cairo University. All cases were subjected to history taking and clinical examination. Stool samples were examined microscopically and by ELISA for
Entamoeba histolytica
,
Giardia lamblia
, and
Cryptosporidium
oocyts. Frequency and duration of both diarrhea and vomiting were significantly higher in immunosuppressed children (
P
< 0.01).
E. histolytica
,
Giardia,
and
Cryptosporidium
were detected in 2 (1.1 %), 29 (15.3 %), and in 9 (4.8 %) samples, respectively, whereas 46 (24.3 %) cases were positive for other parasitic infections. Overall parasitic infections were positive in 86 stool samples (45.5 %): 41 belonging to immunocompetent patients (41 %) and 45 (50.6 %) to the immunosuppressed group though with no statistically important difference. Parasitic infections in Egyptian children with gastroenteritis are still high. No difference in prevalence of infections between immunosuppressed and immunocompetent children, yet clinical data were statistically higher in immunosuppressed patients (
P
< 0.01). ELISA is as good as microscopy and is advantageous in its ability to differentiate between
E
.
histolytica
and
Entamoeba dispar
, thus can aid routine labs in detecting parasitic pathogens.</abstract><cop>London</cop><pub>Springer London</pub><doi>10.1007/s00580-013-1814-5</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1618-5641 |
| ispartof | Comparative clinical pathology, 2014-09, Vol.23 (5), p.1509-1514 |
| issn | 1618-5641 1618-565X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1618150575 |
| source | Springer Nature - Complete Springer Journals |
| subjects | Cryptosporidium Entamoeba dispar Entamoeba histolytica Giardia lamblia Hematology Medicine Medicine & Public Health Oncology Original Article Pathology |
| title | A comparative study on enteric parasitic infections in immunocompetent and immunosuppressed children in Egypt |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-23T01%3A21%3A21IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20comparative%20study%20on%20enteric%20parasitic%20infections%20in%20immunocompetent%20and%20immunosuppressed%20children%20in%20Egypt&rft.jtitle=Comparative%20clinical%20pathology&rft.au=El-Mahallawy,%20Hadir&rft.date=2014-09-01&rft.volume=23&rft.issue=5&rft.spage=1509&rft.epage=1514&rft.pages=1509-1514&rft.issn=1618-5641&rft.eissn=1618-565X&rft_id=info:doi/10.1007/s00580-013-1814-5&rft_dat=%3Cproquest_cross%3E1618150575%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1563696589&rft_id=info:pmid/&rfr_iscdi=true |