Early diagnostic value of soluble triggering receptor expressed on myeloid cell-1 in type 2 diabetic patients with pneumonia

Early diagnostic value of soluble triggering receptor expressed on myeloid cell-1 in type 2 diabetic patients with pneumonia

Objective To investigate the early diagnostic value of soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) in type 2 diabetic patients with pneumonia. Methods 79 cases of type 2 diabetic patients with pneumonia between July 2008 and June 2013 were chosen as the pneumonia group. In the...

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Veröffentlicht in:Guoji Jianyan Yixue Zazhi 2014-01, Vol.35 (7), p.822-823
Hauptverfasser: Luo, Wanying, Zou, Yuanfang, Rong, Xinhua, Chen, Kequan
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creator Luo, Wanying
Zou, Yuanfang
Rong, Xinhua
Chen, Kequan
description Objective To investigate the early diagnostic value of soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) in type 2 diabetic patients with pneumonia. Methods 79 cases of type 2 diabetic patients with pneumonia between July 2008 and June 2013 were chosen as the pneumonia group. In the same period, 80 cases of type 2 diabetes mellitus patients without pneumonia were randomly selected as the control group. Levels of sTREM-1 and procalcitonin (PCT) were measured. Results The levels of sTREM-1 and PCT were significant higher in pneumonia group than those in control group (P
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Methods 79 cases of type 2 diabetic patients with pneumonia between July 2008 and June 2013 were chosen as the pneumonia group. In the same period, 80 cases of type 2 diabetes mellitus patients without pneumonia were randomly selected as the control group. Levels of sTREM-1 and procalcitonin (PCT) were measured. Results The levels of sTREM-1 and PCT were significant higher in pneumonia group than those in control group (P&lt;0.01). The area under the curve (AUC) of sTREM-1 and PCT were 0.932 and 0.921, respectively. The sensibility and specificity of sTREM-1 were 92.4% and 86.3%, while the sensibility and specificity of PCT were 81.0% and 85.0%. Conclusion Serum sTREM-1 and PCT are good biomarkers for early diagnosis of pneumonia in type 2 diabetic patients, and both have higher sensitivity and specificity, while sTREM-1 is better than PCT.</description><identifier>ISSN: 1673-4130</identifier><identifier>DOI: 10.3969/j.issn.1673-4130.2014.07.010</identifier><language>chi</language><ispartof>Guoji Jianyan Yixue Zazhi, 2014-01, Vol.35 (7), p.822-823</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>Luo, Wanying</creatorcontrib><creatorcontrib>Zou, Yuanfang</creatorcontrib><creatorcontrib>Rong, Xinhua</creatorcontrib><creatorcontrib>Chen, Kequan</creatorcontrib><title>Early diagnostic value of soluble triggering receptor expressed on myeloid cell-1 in type 2 diabetic patients with pneumonia</title><title>Guoji Jianyan Yixue Zazhi</title><description>Objective To investigate the early diagnostic value of soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) in type 2 diabetic patients with pneumonia. Methods 79 cases of type 2 diabetic patients with pneumonia between July 2008 and June 2013 were chosen as the pneumonia group. In the same period, 80 cases of type 2 diabetes mellitus patients without pneumonia were randomly selected as the control group. Levels of sTREM-1 and procalcitonin (PCT) were measured. Results The levels of sTREM-1 and PCT were significant higher in pneumonia group than those in control group (P&lt;0.01). The area under the curve (AUC) of sTREM-1 and PCT were 0.932 and 0.921, respectively. The sensibility and specificity of sTREM-1 were 92.4% and 86.3%, while the sensibility and specificity of PCT were 81.0% and 85.0%. Conclusion Serum sTREM-1 and PCT are good biomarkers for early diagnosis of pneumonia in type 2 diabetic patients, and both have higher sensitivity and specificity, while sTREM-1 is better than PCT.</description><issn>1673-4130</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><recordid>eNqVzLFOwzAQxnEPIFFB3-EGBpaYc5MmzYyKeAD2ykmu4SrHNj4HiMTDo0iInemT_vr0U-reoC7bun28aBbx2tRNWVSmRL1DU2lsNBq8Upu_fqO2ItwhYttghfuN-j7a5BYY2I4-SOYePqybCcIZJLi5cwQ58ThSYj9Cop5iDgnoKyYSoQGCh2khF3iAnpwrDLCHvESC3ap2tJrRZiafBT45v0H0NE_Bs71T12frhLa_e6seno-vTy9FTOF9JsmniWVVracwy8nU5mCqtsRD-Y_rD5X_XDc</recordid><startdate>20140101</startdate><enddate>20140101</enddate><creator>Luo, Wanying</creator><creator>Zou, Yuanfang</creator><creator>Rong, Xinhua</creator><creator>Chen, Kequan</creator><scope>7T5</scope><scope>H94</scope></search><sort><creationdate>20140101</creationdate><title>Early diagnostic value of soluble triggering receptor expressed on myeloid cell-1 in type 2 diabetic patients with pneumonia</title><author>Luo, Wanying ; Zou, Yuanfang ; Rong, Xinhua ; Chen, Kequan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-proquest_miscellaneous_16181493083</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>chi</language><creationdate>2014</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Luo, Wanying</creatorcontrib><creatorcontrib>Zou, Yuanfang</creatorcontrib><creatorcontrib>Rong, Xinhua</creatorcontrib><creatorcontrib>Chen, Kequan</creatorcontrib><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><jtitle>Guoji Jianyan Yixue Zazhi</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Luo, Wanying</au><au>Zou, Yuanfang</au><au>Rong, Xinhua</au><au>Chen, Kequan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Early diagnostic value of soluble triggering receptor expressed on myeloid cell-1 in type 2 diabetic patients with pneumonia</atitle><jtitle>Guoji Jianyan Yixue Zazhi</jtitle><date>2014-01-01</date><risdate>2014</risdate><volume>35</volume><issue>7</issue><spage>822</spage><epage>823</epage><pages>822-823</pages><issn>1673-4130</issn><abstract>Objective To investigate the early diagnostic value of soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) in type 2 diabetic patients with pneumonia. Methods 79 cases of type 2 diabetic patients with pneumonia between July 2008 and June 2013 were chosen as the pneumonia group. In the same period, 80 cases of type 2 diabetes mellitus patients without pneumonia were randomly selected as the control group. Levels of sTREM-1 and procalcitonin (PCT) were measured. Results The levels of sTREM-1 and PCT were significant higher in pneumonia group than those in control group (P&lt;0.01). The area under the curve (AUC) of sTREM-1 and PCT were 0.932 and 0.921, respectively. The sensibility and specificity of sTREM-1 were 92.4% and 86.3%, while the sensibility and specificity of PCT were 81.0% and 85.0%. Conclusion Serum sTREM-1 and PCT are good biomarkers for early diagnosis of pneumonia in type 2 diabetic patients, and both have higher sensitivity and specificity, while sTREM-1 is better than PCT.</abstract><doi>10.3969/j.issn.1673-4130.2014.07.010</doi></addata></record>
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title Early diagnostic value of soluble triggering receptor expressed on myeloid cell-1 in type 2 diabetic patients with pneumonia
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