P-cadherin potentiates ligand-dependent EGFR and IGF-1R signaling in dysplastic and malignant oral keratinocytes

Oral and oropharyngeal cancer together constitute the sixth most common cancer worldwide, with over 400,000 new cases diagnosed each year. Early detection is paramount, as the 5-year survival rate for these cancers decreases markedly once tumors have become regionally invasive. In many tissues, incl...

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Veröffentlicht in:Oncology reports 2014-12, Vol.32 (6), p.2541-2548
Hauptverfasser: LYSNE, DESSEREE, JOHNS, JAMES, WALKER, ANDREW, ECKER, RACHEL, FOWLER, CHRISTOPHER, LAWSON, KATHRYN R
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Sprache:eng
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