Ultraviolet radiation suppresses obesity and symptoms of metabolic syndrome independently of vitamin D in mice fed a high-fat diet

The role of vitamin D in curtailing the development of obesity and comorbidities such as the metabolic syndrome (MetS) and type 2 diabetes has received much attention recently. However, clinical trials have failed to conclusively demonstrate the benefits of vitamin D supplementation. In most studies...

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Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2014-11, Vol.63 (11), p.3759-3769
Hauptverfasser:	Geldenhuys, Sian, Hart, Prue H, Endersby, Raelene, Jacoby, Peter, Feelisch, Martin, Weller, Richard B, Matthews, Vance, Gorman, Shelley
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Body Weight - drug effects Body Weight - radiation effects Diabetes Diabetes Mellitus, Type 2 - drug therapy Diabetes Mellitus, Type 2 - etiology Diabetes Mellitus, Type 2 - radiotherapy Diet Diet, High-Fat Glucose Intolerance - drug therapy Glucose Intolerance - metabolism Glucose Intolerance - radiotherapy Insulin Resistance - radiation effects Male Metabolic syndrome Metabolic Syndrome - drug therapy Metabolic Syndrome - etiology Metabolic Syndrome - radiotherapy Mice Mice, Inbred C57BL Nitric oxide Nitric Oxide - metabolism Obesity Obesity - drug therapy Obesity - etiology Obesity - radiotherapy Rodents Skin - drug effects Skin - metabolism Skin - radiation effects Ultraviolet radiation Ultraviolet Rays Vitamin D Vitamin D - analogs & derivatives Vitamin D - therapeutic use
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