EphA3, induced by PC-1/PrLZ, contributes to the malignant progression of prostate cancer

Our previous study revealed the potential linkage of PC-1/PrLZ, a novel isolated prostate-specific gene, to the progression of prostate cancer (PCa) in vitro and in vivo. To gain more insight into the mechanism of PC-1-induced promotion of PCa, expression analysis of differential genes induced by PC...

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Veröffentlicht in:	Oncology reports 2014-12, Vol.32 (6), p.2657-2665
Hauptverfasser:	WU, RUIQIN, WANG, HONGTAO, WANG, JIAN, WANG, PENG, HUANG, FANG, XIE, BANGXIANG, ZHAO, YALI, LI, SHANHU, ZHOU, JIANGUANG
Format:	Artikel
Sprache:	eng
Schlagworte:	Akt signaling pathway Androgens Animals Apoptosis Biomarkers, Tumor - biosynthesis Biomarkers, Tumor - metabolism Carcinogenesis Cell growth Cell Line, Tumor Cell Proliferation - genetics Cloning Development and progression Disease Progression EphA3 Gene Expression Regulation, Neoplastic Genes Genetic aspects Humans Insects Kinases Male Melanoma Metastasis Mice PC-1/PrLZ Phosphoric Diester Hydrolases - genetics Phosphoric Diester Hydrolases - metabolism Physiological aspects Prostate cancer Prostatic Neoplasms - genetics Prostatic Neoplasms - metabolism Prostatic Neoplasms - pathology Protein kinases Proteins Pyrophosphatases - genetics Pyrophosphatases - metabolism Receptor Protein-Tyrosine Kinases - biosynthesis Receptor Protein-Tyrosine Kinases - metabolism Skin cancer Tumors
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