Effects of Gomisin A on Hepatocarcinogenesis by 3’-Methyl-4-dimethylaminoazobenzene in Rats

We examined the effects of gomisin A on tumor promotion in the liver after a short-term feeding of 3’-methyl-4-dimethylaminoazobenzene (3’-MeDAB) to rats, compared with the effects of phenobarbital. Male Donryu rats were fed ad libitum a diet containing 0.06% 3’-MeDAB and 0.03% or 0.01% gomisin A or...

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Veröffentlicht in:	Japanese Journal of Pharmacology 1991, Vol.57(1), pp.71-77
Hauptverfasser:	Miyamoto, Ken-ichi, Wakusawa, Shinya, Nomura, Masaaki, Sanae, Fujiko, Sakai, Ryosuke, Sudo, Kazuhiko, Ohtaki, Yumiko, Takeda, Shigefumi, Fujii, Yuichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anticarcinogenic Agents - pharmacology Biological and medical sciences Body Weight - drug effects Carcinogenesis, carcinogens and anticarcinogens Chemical agents Cyclooctanes Dioxoles Lignans Liver Neoplasms, Experimental - chemically induced Liver Neoplasms, Experimental - pathology Liver Neoplasms, Experimental - prevention & control Male Medical sciences Methyldimethylaminoazobenzene - antagonists & inhibitors Molecular Structure Organ Size - drug effects Phenobarbital - pharmacology Polycyclic Compounds - pharmacology Rats Rats, Inbred Strains Tumors
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