Eckols reduce dental pulp inflammation through the ERK1/2 pathway independent of COX-2 inhibition

Objectives The aim of this study was to elucidate the role of 6‐6 bieckol (EB1) and pholorofucofuroeckol‐A (EB5) from brown seaweed marine algae (Eisenia bicyclis) on lipopolysaccharide (LPS)‐induced inflammation in human dental pulp cells (HDPCs). Methods The cytotoxicity of EB1 and EB5 was examine...

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Veröffentlicht in:	Oral diseases 2014-11, Vol.20 (8), p.827-832
Hauptverfasser:	Paudel, U, Lee, Y-H, Kwon, T-H, Park, N-H, Yun, B-S, Hwang, P-H, Yi, H-K
Format:	Artikel
Sprache:	eng
Schlagworte:	6-6 bieckol Algae Cells, Cultured COX-2 Cyclooxygenase 2 Inhibitors - pharmacology Cytotoxicity Dental Pulp - enzymology Dental Pulp - pathology Dentistry Eisenia bicyclis ERK1/2 Gum disease human dental pulp cells Humans Inflammation - enzymology Inflammation - pathology MAP Kinase Signaling System pholorofucofuroeckol-A Seaweed
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