Differences Between Women and Men with Intermittent Claudication: A Cross-Sectional Study

Intermittent claudication (IC) and its consequences have customarily been underestimated in women. Our study aimed to determine the differences on functional and quality-of-life issues between women and men in a large group of claudicants. This study was an observational, cross-sectional, nonrandomi...

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Veröffentlicht in:Journal of women's health (Larchmont, N.Y. 2002) N.Y. 2002), 2014-10, Vol.23 (10), p.834-841
Hauptverfasser: LOZANO, Francisco S, GONZALEZ-PORRAS, José R, MARCH, José R, CARRASCO, Eduardo, LOBOS, José M
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container_issue 10
container_start_page 834
container_title Journal of women's health (Larchmont, N.Y. 2002)
container_volume 23
creator LOZANO, Francisco S
GONZALEZ-PORRAS, José R
MARCH, José R
CARRASCO, Eduardo
LOBOS, José M
description Intermittent claudication (IC) and its consequences have customarily been underestimated in women. Our study aimed to determine the differences on functional and quality-of-life issues between women and men in a large group of claudicants. This study was an observational, cross-sectional, nonrandomized, multicenter study of 1,641 claudicants (406 women). Information was collected from patients' medical history, a physical examination, the ankle-brachial index (ABI), the Walking Impairment Questionnaire (WIQ), and the European Quality of Life Questionnaire (EQ-5D). On average, women with IC were older than men with IC (70.0 vs. 67.8 years; p
doi_str_mv 10.1089/jwh.2013.4653
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Our study aimed to determine the differences on functional and quality-of-life issues between women and men in a large group of claudicants. This study was an observational, cross-sectional, nonrandomized, multicenter study of 1,641 claudicants (406 women). Information was collected from patients' medical history, a physical examination, the ankle-brachial index (ABI), the Walking Impairment Questionnaire (WIQ), and the European Quality of Life Questionnaire (EQ-5D). On average, women with IC were older than men with IC (70.0 vs. 67.8 years; p<0.001) and tended to have a different socio-occupational status. Women were more likely to be obese and less likely to smoke or have dyslipidemia (p<0.001). Women were notable for their greater prevalence of cardiac insufficiency (p=0.016) and arrhythmias (p<0.001) and a lower prevalence of ischemic cardiopathy and acute myocardial infarction (p<0.001). At the same time, there was a significantly higher level of osteoarticular diseases in women: arthrosis (p<0.001), arthritis (p<0.001), and lumbar pathology (p=0.006). All the symptoms evaluated that were associated with IC were more frequent in women (p<0.05). The mean ABI was similar in claudicant women and men. Conversely, the parameter estimates of the WIQ were significantly lower in women (by 4.3%, and 6.5%, respectively; p=0.003). Likewise, the EQ-5D score was 7% lower in women than in men (from 0.52 to 0.59; p<0.001). Women claudicants have higher risk factors and more frequent cardiovascular comorbidity than men do. Women have a lower capacity for exercise and a poorer quality of life than male claudicants, despite having a similar ABI. These poorer outcomes in women can be partially explained by the presence of greater osteoarticular comorbidity.]]></description><identifier>ISSN: 1540-9996</identifier><identifier>EISSN: 1931-843X</identifier><identifier>DOI: 10.1089/jwh.2013.4653</identifier><identifier>PMID: 25238019</identifier><language>eng</language><publisher>Larchmont, NY: Mary Ann Liebert</publisher><subject>Activities of Daily Living - psychology ; Age Distribution ; Aged ; Ankle Brachial Index ; Biological and medical sciences ; Cardiovascular Diseases - epidemiology ; Comorbidity ; Cross-Sectional Studies ; Exercise ; Female ; Humans ; Intermittent Claudication - epidemiology ; Intermittent Claudication - physiopathology ; Intermittent Claudication - psychology ; Male ; Medical sciences ; Middle Aged ; Prevention and actions ; Public health. Hygiene ; Public health. 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Our study aimed to determine the differences on functional and quality-of-life issues between women and men in a large group of claudicants. This study was an observational, cross-sectional, nonrandomized, multicenter study of 1,641 claudicants (406 women). Information was collected from patients' medical history, a physical examination, the ankle-brachial index (ABI), the Walking Impairment Questionnaire (WIQ), and the European Quality of Life Questionnaire (EQ-5D). On average, women with IC were older than men with IC (70.0 vs. 67.8 years; p<0.001) and tended to have a different socio-occupational status. Women were more likely to be obese and less likely to smoke or have dyslipidemia (p<0.001). Women were notable for their greater prevalence of cardiac insufficiency (p=0.016) and arrhythmias (p<0.001) and a lower prevalence of ischemic cardiopathy and acute myocardial infarction (p<0.001). At the same time, there was a significantly higher level of osteoarticular diseases in women: arthrosis (p<0.001), arthritis (p<0.001), and lumbar pathology (p=0.006). All the symptoms evaluated that were associated with IC were more frequent in women (p<0.05). The mean ABI was similar in claudicant women and men. Conversely, the parameter estimates of the WIQ were significantly lower in women (by 4.3%, and 6.5%, respectively; p=0.003). Likewise, the EQ-5D score was 7% lower in women than in men (from 0.52 to 0.59; p<0.001). Women claudicants have higher risk factors and more frequent cardiovascular comorbidity than men do. Women have a lower capacity for exercise and a poorer quality of life than male claudicants, despite having a similar ABI. These poorer outcomes in women can be partially explained by the presence of greater osteoarticular comorbidity.]]></description><subject>Activities of Daily Living - psychology</subject><subject>Age Distribution</subject><subject>Aged</subject><subject>Ankle Brachial Index</subject><subject>Biological and medical sciences</subject><subject>Cardiovascular Diseases - epidemiology</subject><subject>Comorbidity</subject><subject>Cross-Sectional Studies</subject><subject>Exercise</subject><subject>Female</subject><subject>Humans</subject><subject>Intermittent Claudication - epidemiology</subject><subject>Intermittent Claudication - physiopathology</subject><subject>Intermittent Claudication - psychology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Prevention and actions</subject><subject>Public health. Hygiene</subject><subject>Public health. Hygiene-occupational medicine</subject><subject>Quality of Life</subject><subject>Risk Factors</subject><subject>Sex Distribution</subject><subject>Socioeconomic Factors</subject><subject>Specific populations (family, woman, child, elderly...)</subject><subject>Surveys and Questionnaires</subject><subject>Walking</subject><issn>1540-9996</issn><issn>1931-843X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkE1Lw0AQhhdRbK0evUougpfUnd002fVW6ydUPFRRT2GzO0tT8lGzG0r_vQmtepl3GB5ehoeQc6BjoEJerzbLMaPAx1E84QdkCJJDKCL-edjtk4iGUsp4QE6cW1HKGFB6TAZswrigIIfk6y63FhusNLrgFv0GsQo-6rKbqjLBS5eb3C-D58pjU-beY-WDWaFak2vl87q6CabBrKmdCxeo-4MqgoVvzfaUHFlVODzb54i8P9y_zZ7C-evj82w6DzVn3IdG2ERIpEwaLWWGEGGSZZgkKgNqJyJWVIPUkEWGAjMJFdRYaSGKmNbWxHxErna966b-btH5tMydxqJQFdatSyEGLqMEQHRouEN1_3CDNl03eamabQo07W2mnc20t5n2Njv-Yl_dZiWaP_pXXwdc7gHltCpsoyqdu39OSCZEzPkPPlh9mA</recordid><startdate>20141001</startdate><enddate>20141001</enddate><creator>LOZANO, Francisco S</creator><creator>GONZALEZ-PORRAS, José R</creator><creator>MARCH, José R</creator><creator>CARRASCO, Eduardo</creator><creator>LOBOS, José M</creator><general>Mary Ann Liebert</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20141001</creationdate><title>Differences Between Women and Men with Intermittent Claudication: A Cross-Sectional Study</title><author>LOZANO, Francisco S ; GONZALEZ-PORRAS, José R ; MARCH, José R ; CARRASCO, Eduardo ; LOBOS, José M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c323t-d8f789e029dc99be14e7bbe77ab10f586a0c19c1b4d012d7080df9f1442ccfd63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Activities of Daily Living - psychology</topic><topic>Age Distribution</topic><topic>Aged</topic><topic>Ankle Brachial Index</topic><topic>Biological and medical sciences</topic><topic>Cardiovascular Diseases - epidemiology</topic><topic>Comorbidity</topic><topic>Cross-Sectional Studies</topic><topic>Exercise</topic><topic>Female</topic><topic>Humans</topic><topic>Intermittent Claudication - epidemiology</topic><topic>Intermittent Claudication - physiopathology</topic><topic>Intermittent Claudication - psychology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Prevention and actions</topic><topic>Public health. Hygiene</topic><topic>Public health. Hygiene-occupational medicine</topic><topic>Quality of Life</topic><topic>Risk Factors</topic><topic>Sex Distribution</topic><topic>Socioeconomic Factors</topic><topic>Specific populations (family, woman, child, elderly...)</topic><topic>Surveys and Questionnaires</topic><topic>Walking</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>LOZANO, Francisco S</creatorcontrib><creatorcontrib>GONZALEZ-PORRAS, José R</creatorcontrib><creatorcontrib>MARCH, José R</creatorcontrib><creatorcontrib>CARRASCO, Eduardo</creatorcontrib><creatorcontrib>LOBOS, José M</creatorcontrib><creatorcontrib>VITAL Investigators</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of women's health (Larchmont, N.Y. 2002)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>LOZANO, Francisco S</au><au>GONZALEZ-PORRAS, José R</au><au>MARCH, José R</au><au>CARRASCO, Eduardo</au><au>LOBOS, José M</au><aucorp>VITAL Investigators</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Differences Between Women and Men with Intermittent Claudication: A Cross-Sectional Study</atitle><jtitle>Journal of women's health (Larchmont, N.Y. 2002)</jtitle><addtitle>J Womens Health (Larchmt)</addtitle><date>2014-10-01</date><risdate>2014</risdate><volume>23</volume><issue>10</issue><spage>834</spage><epage>841</epage><pages>834-841</pages><issn>1540-9996</issn><eissn>1931-843X</eissn><abstract><![CDATA[Intermittent claudication (IC) and its consequences have customarily been underestimated in women. Our study aimed to determine the differences on functional and quality-of-life issues between women and men in a large group of claudicants. This study was an observational, cross-sectional, nonrandomized, multicenter study of 1,641 claudicants (406 women). Information was collected from patients' medical history, a physical examination, the ankle-brachial index (ABI), the Walking Impairment Questionnaire (WIQ), and the European Quality of Life Questionnaire (EQ-5D). On average, women with IC were older than men with IC (70.0 vs. 67.8 years; p<0.001) and tended to have a different socio-occupational status. Women were more likely to be obese and less likely to smoke or have dyslipidemia (p<0.001). Women were notable for their greater prevalence of cardiac insufficiency (p=0.016) and arrhythmias (p<0.001) and a lower prevalence of ischemic cardiopathy and acute myocardial infarction (p<0.001). At the same time, there was a significantly higher level of osteoarticular diseases in women: arthrosis (p<0.001), arthritis (p<0.001), and lumbar pathology (p=0.006). All the symptoms evaluated that were associated with IC were more frequent in women (p<0.05). The mean ABI was similar in claudicant women and men. Conversely, the parameter estimates of the WIQ were significantly lower in women (by 4.3%, and 6.5%, respectively; p=0.003). Likewise, the EQ-5D score was 7% lower in women than in men (from 0.52 to 0.59; p<0.001). Women claudicants have higher risk factors and more frequent cardiovascular comorbidity than men do. Women have a lower capacity for exercise and a poorer quality of life than male claudicants, despite having a similar ABI. These poorer outcomes in women can be partially explained by the presence of greater osteoarticular comorbidity.]]></abstract><cop>Larchmont, NY</cop><pub>Mary Ann Liebert</pub><pmid>25238019</pmid><doi>10.1089/jwh.2013.4653</doi><tpages>8</tpages></addata></record>
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subjects Activities of Daily Living - psychology
Age Distribution
Aged
Ankle Brachial Index
Biological and medical sciences
Cardiovascular Diseases - epidemiology
Comorbidity
Cross-Sectional Studies
Exercise
Female
Humans
Intermittent Claudication - epidemiology
Intermittent Claudication - physiopathology
Intermittent Claudication - psychology
Male
Medical sciences
Middle Aged
Prevention and actions
Public health. Hygiene
Public health. Hygiene-occupational medicine
Quality of Life
Risk Factors
Sex Distribution
Socioeconomic Factors
Specific populations (family, woman, child, elderly...)
Surveys and Questionnaires
Walking
title Differences Between Women and Men with Intermittent Claudication: A Cross-Sectional Study
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