Microarray-based detection and expression analysis of extracellular matrix proteins in drug-resistant ovarian cancer cell lines

Ovarian cancer is the most lethal gynecological malignancy. Multiple drug resistance (MDR) development leads to resistance of cancer cells to chemotherapy. Microarray methods can provide information regarding new candidate genes that can play a role in resistance to cytostatic drugs. Extracellular m...

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Veröffentlicht in:	Oncology reports 2014-11, Vol.32 (5), p.1981-1990
Hauptverfasser:	JANUCHOWSKI, RADOSŁAW, ZAWIERUCHA, PIOTR, RUCIŃSKI, MARCIN, ZABEL, MACIEJ
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - pharmacology Apoptosis Cancer Cancer therapies cDNA microarray Cell growth Cell Line, Tumor Chemotherapy Drug resistance Drug Resistance, Neoplasm Extracellular matrix Extracellular Matrix Proteins - genetics Female Gene expression Gene Expression Profiling - methods Gene Expression Regulation, Neoplastic Genetic aspects Genomes Humans Metastasis multidrug resistance Oligonucleotide Array Sequence Analysis - methods Oncology, Experimental Ovarian cancer Ovarian Neoplasms - drug therapy Ovarian Neoplasms - genetics Penicillin Physiological aspects Proteins
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