Effect of period of exposure on the developmental toxicity of butyl benzyl phthalate in rats

The objective of the present study was to determine if periods of exposure would modify the developmental toxicity of butyl benzyl phthalate (BBP). Pregnant Wistar rats were given BBP at a dose of 2.0% in the diet on days 0–20, days 0–7, days 7–16 or days 16–20 of pregnancy. Food consumption and bod...

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Veröffentlicht in:	Journal of applied toxicology 1992-02, Vol.12 (1), p.57-61
Hauptverfasser:	Ema, Makoto, Itami, Takafumi, Kawasaki, Hironoshin
Format:	Artikel
Sprache:	eng
Schlagworte:	Abnormalities, Drug-Induced - etiology Animals Biological and medical sciences Bone and Bones - abnormalities butyl benzyl phthalate cleft palate Corpus Luteum - drug effects developmental toxicity Eating - drug effects Embryo Implantation - drug effects embryolethality Embryology: invertebrates and vertebrates. Teratology Embryonic and Fetal Development - drug effects Female Fundamental and applied biological sciences. Psychology Kidney Pelvis - abnormalities Male phthalic acid ester Phthalic Acids - toxicity plasticizer Pregnancy Prenatal Exposure Delayed Effects rat Rats Rats, Inbred Strains teratogenicity Teratology. Teratogens Time Factors
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