Effects of soman-induced seizures on different extracellular amino acid levels and on glutamate uptake in rat hippocampus

Extracellular amino acid levels in CA 3 and CA 1 fields of rat hippocampus, an area highly sensitive to seizures, were determined by intracranial microdialysis during seizures induced by systemic administration of soman ( o-1,2,2-trimethylpropyl methylphosphonofluoridate), a potent inhibitor of acet...

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Veröffentlicht in:	Brain research 1991-11, Vol.563 (1), p.234-240
Hauptverfasser:	Lallement, Guy, Carpentier, Pierre, Collet, Agnès, Pernot-Marino, Irmine, Baubichon, Dominique, Blanchet, Guy
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acid Amino Acids - metabolism Animals Brain dialysis Dialysis Glutamate uptake Glutamates - metabolism Hippocampus Hippocampus - drug effects Hippocampus - metabolism Male Neuroglia - drug effects Neuroglia - metabolism Neurons - drug effects Neurons - metabolism Perfusion Rats Rats, Inbred Strains Seizure Seizures - chemically induced Seizures - metabolism Soman Soman - pharmacology
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