Further investigations into the pathophysiology of MPTP-induced parkinsonism in the primate: an intracerebral microdialysis study of γ-aminobutyric acid in the lateral segment of the globus pallidus

The technique of intracerebral microdialysis has been employed to examine the extracellular level of γ-aminobutyric acid (GABA) within the lateral segment of the globus pallidus of two cynomolgus monkeys, before and after the induction of parkinsonism with N-methyl-4-phenyl-1,2,3,6-tetrahydropyridin...

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Veröffentlicht in:	Brain research 1991-11, Vol.563 (1), p.278-280
Hauptverfasser:	Robertson, R.G., Graham, W.C., Sambrook, M.A., Crossman, A.R.
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Animals Biological and medical sciences Chromatography, High Pressure Liquid Dialysis Extracellular Space - drug effects Extracellular Space - metabolism Female gamma-Aminobutyric Acid - metabolism Globus pallidus Globus Pallidus - chemistry Globus Pallidus - drug effects Globus Pallidus - metabolism Macaca fascicularis Male Medical sciences Microdialysis N-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Nervous system involvement in other diseases. Miscellaneous Neurology Parkinson Disease, Secondary - chemically induced Parkinson Disease, Secondary - metabolism Parkinson Disease, Secondary - physiopathology Parkinsonism Primate γ-Aminobutyric acid
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