The analysis of deregulated expression and methylation of the PER2 genes in gliomas

Growing evidence shows that disruption of circadian rhythm may be a risk factor in the development of glioma. However, the molecular mechanisms of genes controlling circadian rhythm in glioma cells have not been explored and differential expression of the circadian clock genes in glioma and non-tumo...

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Veröffentlicht in:	Journal of cancer research and therapeutics 2014-07, Vol.10 (3), p.636-640
Hauptverfasser:	Fan, Wang, Chen, Xiaowei, Li, Caiyan, Chen, Lvan, Liu, Pingfei, Chen, Zhijun
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Apoptosis Biotechnology Cancer Cell cycle Child Circadian rhythm Deoxyribonucleic acid Development and progression DNA DNA Methylation Female Gene expression Gene Expression Regulation, Neoplastic Genetic aspects Genetic research Genetic testing Glioma - genetics Glioma - metabolism Glioma - pathology Gliomas Humans Male Middle Aged Oncology, Experimental Patients Period Circadian Proteins - genetics Period Circadian Proteins - metabolism Promoter Regions, Genetic Proteins Studies Tumors Young Adult
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