An update on the interaction between the serotonin transporter promoter variant (5-HTTLPR), stress and depression, plus an exploration of non-confirming findings

•A meta analysis was conducted on 81 studies of the 5-HTTLPR, stress and depression.•The overall association was confirmed.•26% of studies failed to show significant associations.•Nearly 10% of studies showed opposite results.•Methodologies were not different across these findings. In the three year...

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