The BRAF mutation is associated with the prognosis in colorectal cancer

Background Two members of the Ras/Raf signaling pathway, KRAS and B-raf, are suspected to be involved in the stepwise progression of colorectal cancer (CRC) tumorigenesis. Objective We compared the KRAS and BRAF mutation status of CRC patients with their clinicopathological characteristics and exami...

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Veröffentlicht in:	Journal of cancer research and clinical oncology 2014-11, Vol.140 (11), p.1863-1871
Hauptverfasser:	Ahn, Tae Sung, Jeong, Dongjun, Son, Myoung Won, Jung, Haeil, Park, Soyoung, Kim, Hyungjoo, Bae, Sang Byung, Kim, Han Jo, Jeon, Young-Woo, Lee, Moon Soo, Baek, Moo-Jun
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Research Colorectal cancer Colorectal Neoplasms - diagnosis Colorectal Neoplasms - genetics Colorectal Neoplasms - mortality Female Genetic Association Studies Genetic Predisposition to Disease Hematology Humans Internal Medicine Kaplan-Meier Estimate Male Medical prognosis Medicine Medicine & Public Health Middle Aged Mutation Mutation, Missense Oncology Original Article – Cancer Research Prognosis Proportional Hazards Models Proteins Proto-Oncogene Proteins - genetics Proto-Oncogene Proteins B-raf - genetics Proto-Oncogene Proteins p21(ras) ras Proteins - genetics Tumorigenesis
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