Influence of preoperative chemoradiotherapy on changes of epidermal growth factor receptor expression in patients treated by preoperative chemoradiotherapy for local advanced rectal carcinoma

The aim of this retrospective study was to determine the prognostic impact of expression of epidermal growth factor receptor (EGFR) changes during neoadjuvant chemoradiotherapy in patients with locally advanced rectal adenocarcinoma. One hundred and three patients with locally advanced rectal adenoc...

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Veröffentlicht in:	Klinická onkologie 2014, Vol.27 (5), p.361-366
Hauptverfasser:	Richter, I, Dvořák, J, Blüml, A, Cermáková, E, Bartoš, J, Urbanec, M, Sitorová, V, Ryška, A, Sirák, I, Buka, D, Ferko, A, Melichar, B, Petera, J
Format:	Artikel
Sprache:	cze ; eng
Schlagworte:	Adenocarcinoma - mortality Adenocarcinoma - pathology Adenocarcinoma - therapy Adult Aged Antimetabolites, Antineoplastic - therapeutic use Capecitabine Chemoradiotherapy, Adjuvant - methods Deoxycytidine - administration & dosage Deoxycytidine - analogs & derivatives Disease-Free Survival Drug Administration Schedule Female Fluorouracil - administration & dosage Fluorouracil - analogs & derivatives Humans Male Middle Aged Neoadjuvant Therapy Neoplasm Recurrence, Local - metabolism Neoplasm Recurrence, Local - mortality Preoperative Care Prognosis Radiotherapy Dosage Receptor, Epidermal Growth Factor - metabolism Rectal Neoplasms - mortality Rectal Neoplasms - pathology Rectal Neoplasms - therapy Retrospective Studies
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