LASP-1 promotes tumor proliferation and metastasis and is an independent unfavorable prognostic factor in gastric cancer

Purpose The LIM and SH3 protein 1 (LASP-1) is a focal adhesion protein, and its expression has been reported to be increased in many malignant tumors. However, the role of LASP-1 in gastric cancer is still unknown. The aim of this study was to determine the relationship of LASP-1 expression with the...

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Veröffentlicht in:	Journal of cancer research and clinical oncology 2014-11, Vol.140 (11), p.1891-1899
Hauptverfasser:	Zheng, Jie, Yu, Shuna, Qiao, Yanchun, Zhang, Hongxia, Liang, Shujuan, Wang, Hailiang, Liu, Yuqing, Zhou, Fenghua, Jiang, Jiying, Lu, Shijun
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing - physiology Animals Cancer Research Cell Line, Tumor Cell Movement Cell Proliferation Cellular biology Cytoskeletal Proteins - physiology Female Gastric cancer Hematology Humans Internal Medicine Kaplan-Meier Estimate LIM Domain Proteins - physiology Lymphatic Metastasis Male Medical prognosis Medicine Medicine & Public Health Metastasis Mice, SCID Middle Aged Neoplasm Transplantation Oncology Original Article – Cancer Research Prognosis Protein expression Stomach Neoplasms - metabolism Stomach Neoplasms - mortality Stomach Neoplasms - pathology Tumor Suppressor Protein p53 - metabolism
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