Defining Anxious Depression in Later Life: A Scaring Heterogeneity in Results
Background Anxiety in depression is challenging as it results in more functional impairment and a worse prognosis. No consensus exists on the definition of anxious depression. Methods In 359 older patients with major depressive disorder, we examined the agreement between anxious depression based on...
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| Veröffentlicht in: | The American journal of geriatric psychiatry 2014-11, Vol.22 (11), p.1375-1378 |
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| container_title | The American journal of geriatric psychiatry |
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| creator | van der Veen, Date C., M.Sc Comijs, Hannie C., Ph.D van Zelst, Willeke H., Ph.D Schoevers, Robert A., Ph.D Oude Voshaar, Richard C., Ph.D |
| description | Background Anxiety in depression is challenging as it results in more functional impairment and a worse prognosis. No consensus exists on the definition of anxious depression. Methods In 359 older patients with major depressive disorder, we examined the agreement between anxious depression based on different combinations of comorbid anxiety disorders and anxious depression based on high level of anxiety symptoms measured by self-report questionnaires. Results Agreement between the definitions of anxious depression was poor, as indicated by κ statistics ranging between 0.06 and 0.23. Conclusion Accepted criteria for anxious depression classify completely different patients as being anxious depressed. This may explain inconsistent results of previous studies on anxious depression. Moreover, progress in this research field is hampered, as studies using different definitions cannot be pooled in meta-analyses. |
| doi_str_mv | 10.1016/j.jagp.2014.02.012 |
| format | Article |
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No consensus exists on the definition of anxious depression. Methods In 359 older patients with major depressive disorder, we examined the agreement between anxious depression based on different combinations of comorbid anxiety disorders and anxious depression based on high level of anxiety symptoms measured by self-report questionnaires. Results Agreement between the definitions of anxious depression was poor, as indicated by κ statistics ranging between 0.06 and 0.23. Conclusion Accepted criteria for anxious depression classify completely different patients as being anxious depressed. This may explain inconsistent results of previous studies on anxious depression. Moreover, progress in this research field is hampered, as studies using different definitions cannot be pooled in meta-analyses.</description><identifier>ISSN: 1064-7481</identifier><identifier>EISSN: 1545-7214</identifier><identifier>DOI: 10.1016/j.jagp.2014.02.012</identifier><identifier>PMID: 24703569</identifier><language>eng</language><publisher>England: Elsevier Inc</publisher><subject>Age Factors ; Aged ; Aged, 80 and over ; Anxiety Disorders - complications ; Anxiety Disorders - diagnosis ; anxious depression ; comorbidity ; depression ; Depressive Disorder, Major - complications ; Depressive Disorder, Major - diagnosis ; Female ; Humans ; Internal Medicine ; late-life depression ; Male ; Middle Aged ; Mixed anxiety depression ; Psychiatric Status Rating Scales</subject><ispartof>The American journal of geriatric psychiatry, 2014-11, Vol.22 (11), p.1375-1378</ispartof><rights>American Association for Geriatric Psychiatry</rights><rights>2014 American Association for Geriatric Psychiatry</rights><rights>Copyright © 2014 American Association for Geriatric Psychiatry. Published by Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c481t-b23031001bc507e4302ea3ead99cc896fafca2c669c0d1c12b518952a174bad13</citedby><cites>FETCH-LOGICAL-c481t-b23031001bc507e4302ea3ead99cc896fafca2c669c0d1c12b518952a174bad13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24703569$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>van der Veen, Date C., M.Sc</creatorcontrib><creatorcontrib>Comijs, Hannie C., Ph.D</creatorcontrib><creatorcontrib>van Zelst, Willeke H., Ph.D</creatorcontrib><creatorcontrib>Schoevers, Robert A., Ph.D</creatorcontrib><creatorcontrib>Oude Voshaar, Richard C., Ph.D</creatorcontrib><title>Defining Anxious Depression in Later Life: A Scaring Heterogeneity in Results</title><title>The American journal of geriatric psychiatry</title><addtitle>Am J Geriatr Psychiatry</addtitle><description>Background Anxiety in depression is challenging as it results in more functional impairment and a worse prognosis. No consensus exists on the definition of anxious depression. Methods In 359 older patients with major depressive disorder, we examined the agreement between anxious depression based on different combinations of comorbid anxiety disorders and anxious depression based on high level of anxiety symptoms measured by self-report questionnaires. Results Agreement between the definitions of anxious depression was poor, as indicated by κ statistics ranging between 0.06 and 0.23. Conclusion Accepted criteria for anxious depression classify completely different patients as being anxious depressed. This may explain inconsistent results of previous studies on anxious depression. Moreover, progress in this research field is hampered, as studies using different definitions cannot be pooled in meta-analyses.</description><subject>Age Factors</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Anxiety Disorders - complications</subject><subject>Anxiety Disorders - diagnosis</subject><subject>anxious depression</subject><subject>comorbidity</subject><subject>depression</subject><subject>Depressive Disorder, Major - complications</subject><subject>Depressive Disorder, Major - diagnosis</subject><subject>Female</subject><subject>Humans</subject><subject>Internal Medicine</subject><subject>late-life depression</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Mixed anxiety depression</subject><subject>Psychiatric Status Rating Scales</subject><issn>1064-7481</issn><issn>1545-7214</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kcFq3DAQhkVpaNK0L5BD8LEXuzOyLNshFJakbQIbAkl7FrI8XuR65a1kh-7bV2bTHnLISUJ8_6D5fsbOEDIElJ_7rNebXcYBRQY8A-Rv2AkWokhLjuJtvIMUaSkqPGbvQ-gBQNZSvGPHXJSQF7I-YXfX1Fln3SZZuT92nENyTTtPIdjRJdYlaz2RT9a2o4tklTwa7Rf2huLruCFHdtov2AOFeZjCB3bU6SHQx-fzlP389vXH1U26vv9-e7VapyZ-ZkobnkOOANiYAkoSOXDSOem2ro2patnpzmhupKwNtGiQNwVWdcE1lqLRLean7NNh7s6Pv2cKk9raYGgYtKO4g0KJKDmUFY8oP6DGjyF46tTO2632e4WgFo2qV4tGtWhUwFXUGEPnz_PnZkvt_8g_bxG4PAAUt3yy5FUwlpyh1noyk2pH-_r8Ly_iZogtGD38oj2Ffpy9i_4UqhAD6nEpcukRReyw4mX-F5Wol04</recordid><startdate>20141101</startdate><enddate>20141101</enddate><creator>van der Veen, Date C., M.Sc</creator><creator>Comijs, Hannie C., Ph.D</creator><creator>van Zelst, Willeke H., Ph.D</creator><creator>Schoevers, Robert A., Ph.D</creator><creator>Oude Voshaar, Richard C., Ph.D</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20141101</creationdate><title>Defining Anxious Depression in Later Life: A Scaring Heterogeneity in Results</title><author>van der Veen, Date C., M.Sc ; Comijs, Hannie C., Ph.D ; van Zelst, Willeke H., Ph.D ; Schoevers, Robert A., Ph.D ; Oude Voshaar, Richard C., Ph.D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c481t-b23031001bc507e4302ea3ead99cc896fafca2c669c0d1c12b518952a174bad13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Age Factors</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Anxiety Disorders - complications</topic><topic>Anxiety Disorders - diagnosis</topic><topic>anxious depression</topic><topic>comorbidity</topic><topic>depression</topic><topic>Depressive Disorder, Major - complications</topic><topic>Depressive Disorder, Major - diagnosis</topic><topic>Female</topic><topic>Humans</topic><topic>Internal Medicine</topic><topic>late-life depression</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Mixed anxiety depression</topic><topic>Psychiatric Status Rating Scales</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>van der Veen, Date C., M.Sc</creatorcontrib><creatorcontrib>Comijs, Hannie C., Ph.D</creatorcontrib><creatorcontrib>van Zelst, Willeke H., Ph.D</creatorcontrib><creatorcontrib>Schoevers, Robert A., Ph.D</creatorcontrib><creatorcontrib>Oude Voshaar, Richard C., Ph.D</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of geriatric psychiatry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>van der Veen, Date C., M.Sc</au><au>Comijs, Hannie C., Ph.D</au><au>van Zelst, Willeke H., Ph.D</au><au>Schoevers, Robert A., Ph.D</au><au>Oude Voshaar, Richard C., Ph.D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Defining Anxious Depression in Later Life: A Scaring Heterogeneity in Results</atitle><jtitle>The American journal of geriatric psychiatry</jtitle><addtitle>Am J Geriatr Psychiatry</addtitle><date>2014-11-01</date><risdate>2014</risdate><volume>22</volume><issue>11</issue><spage>1375</spage><epage>1378</epage><pages>1375-1378</pages><issn>1064-7481</issn><eissn>1545-7214</eissn><abstract>Background Anxiety in depression is challenging as it results in more functional impairment and a worse prognosis. No consensus exists on the definition of anxious depression. Methods In 359 older patients with major depressive disorder, we examined the agreement between anxious depression based on different combinations of comorbid anxiety disorders and anxious depression based on high level of anxiety symptoms measured by self-report questionnaires. Results Agreement between the definitions of anxious depression was poor, as indicated by κ statistics ranging between 0.06 and 0.23. Conclusion Accepted criteria for anxious depression classify completely different patients as being anxious depressed. This may explain inconsistent results of previous studies on anxious depression. Moreover, progress in this research field is hampered, as studies using different definitions cannot be pooled in meta-analyses.</abstract><cop>England</cop><pub>Elsevier Inc</pub><pmid>24703569</pmid><doi>10.1016/j.jagp.2014.02.012</doi><tpages>4</tpages></addata></record> |
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| subjects | Age Factors Aged Aged, 80 and over Anxiety Disorders - complications Anxiety Disorders - diagnosis anxious depression comorbidity depression Depressive Disorder, Major - complications Depressive Disorder, Major - diagnosis Female Humans Internal Medicine late-life depression Male Middle Aged Mixed anxiety depression Psychiatric Status Rating Scales |
| title | Defining Anxious Depression in Later Life: A Scaring Heterogeneity in Results |
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