In Patients with Chronic Stable Angina, Secondary Prevention Appears Better in the Very Old Compared to Younger Patients: The Coronary Artery Disease in gENeral practiCE (CADENCE) Substudy
Background With our aging communities and the increased prevalence of coronary heart disease (CAD) with age, the impact of this disease in the very old warrants further investigation. Objective To assess health outcomes and the attainment of guideline-based secondary prevention targets in the very o...
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| Veröffentlicht in: | Heart, lung & circulation lung & circulation, 2013-02, Vol.22 (2), p.116-121 |
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| creator | Rajendran, Sharmalar, FRACP, PhD Visvanathan, Renuka, FRACP, PhD Tavella, Rosanna, BSc(Hons), PhD Weekes, Andrew J., BMBS Morgan, Claire, BSc Physio Beltrame, John F., FRACP, PhD |
| description | Background With our aging communities and the increased prevalence of coronary heart disease (CAD) with age, the impact of this disease in the very old warrants further investigation. Objective To assess health outcomes and the attainment of guideline-based secondary prevention targets in the very old (>80 years, n = 482) as compared to young ( 0.05]. Also blood pressure, lipid, diabetic and body habitus targets were more often achieved in the very old and elderly patients compared to young stable angina patients. Conclusion Despite similar symptomatic status and greater physical limitations, the very old reported a better quality of life and more often achieved treatment targets than young stable angina patients. Failure to improve secondary prevention measures in younger age groups may potentially contribute to increased morbidity in older age, and failure to achieve ‘Healthy Ageing’. |
| doi_str_mv | 10.1016/j.hlc.2012.09.003 |
| format | Article |
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Objective To assess health outcomes and the attainment of guideline-based secondary prevention targets in the very old (>80 years, n = 482) as compared to young (<65 years, n = 582) and elderly (between 65 and 80 years, n = 932) patients, all of whom had chronic stable angina. Design The coronary artery disease in general practice (CADENCE) study was a cluster-stratified cross-sectional survey. This study reports on health outcomes quantitated using the Seattle Angina Questionnaire and guideline targets achieved for blood pressure, smoking, lipids, diabetic control and body habitus. Settings and participants 2031 stable angina patients were recruited from 207 primary care practices. Results Despite similar angina frequency scores, the very old were more physically impaired by their angina than both the young and elderly [76 ± 25 (Young) vs. 70 ± 26 (Elderly) vs. 63 ± 28 (Very old), p < 0.05 for both comparisons]. However, the very old had better quality of life scores than young stable angina patients [72 ± 24 vs. 65 ± 25, p < 0.05] and were similar to the elderly [72 ± 24 vs. 72 ± 23, p > 0.05]. Also blood pressure, lipid, diabetic and body habitus targets were more often achieved in the very old and elderly patients compared to young stable angina patients. Conclusion Despite similar symptomatic status and greater physical limitations, the very old reported a better quality of life and more often achieved treatment targets than young stable angina patients. Failure to improve secondary prevention measures in younger age groups may potentially contribute to increased morbidity in older age, and failure to achieve ‘Healthy Ageing’.</description><identifier>ISSN: 1443-9506</identifier><identifier>EISSN: 1444-2892</identifier><identifier>DOI: 10.1016/j.hlc.2012.09.003</identifier><identifier>PMID: 23137911</identifier><language>eng</language><publisher>Australia: Elsevier B.V</publisher><subject>80 and over ; Age Factors ; Aged ; Angina ; Angina, Stable - epidemiology ; Angina, Stable - physiopathology ; Angina, Stable - prevention & control ; Australia - epidemiology ; Blood Pressure ; Cardiovascular ; Chronic Disease ; Coronary Artery Disease - epidemiology ; Cross-Sectional Studies ; Diabetes Mellitus - blood ; Diabetes Mellitus - epidemiology ; General Practice ; Glycated Hemoglobin A - metabolism ; Humans ; Hypercholesterolemia - blood ; Hypercholesterolemia - epidemiology ; Hypertension - epidemiology ; Hypertension - physiopathology ; Middle Aged ; Obesity - epidemiology ; Practice Guidelines as Topic ; Quality of Life ; Secondary Prevention ; Smoking - epidemiology ; Stable ; Surveys and Questionnaires</subject><ispartof>Heart, lung & circulation, 2013-02, Vol.22 (2), p.116-121</ispartof><rights>Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ)</rights><rights>2012 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ)</rights><rights>Copyright © 2012 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ). Published by Elsevier B.V. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c408t-4d83efc9734b9c0cf605525c130a8c4424e10a8f3c9be2f6e06f38b3ad18123f3</citedby><cites>FETCH-LOGICAL-c408t-4d83efc9734b9c0cf605525c130a8c4424e10a8f3c9be2f6e06f38b3ad18123f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.hlc.2012.09.003$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23137911$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rajendran, Sharmalar, FRACP, PhD</creatorcontrib><creatorcontrib>Visvanathan, Renuka, FRACP, PhD</creatorcontrib><creatorcontrib>Tavella, Rosanna, BSc(Hons), PhD</creatorcontrib><creatorcontrib>Weekes, Andrew J., BMBS</creatorcontrib><creatorcontrib>Morgan, Claire, BSc Physio</creatorcontrib><creatorcontrib>Beltrame, John F., FRACP, PhD</creatorcontrib><title>In Patients with Chronic Stable Angina, Secondary Prevention Appears Better in the Very Old Compared to Younger Patients: The Coronary Artery Disease in gENeral practiCE (CADENCE) Substudy</title><title>Heart, lung & circulation</title><addtitle>Heart Lung Circ</addtitle><description>Background With our aging communities and the increased prevalence of coronary heart disease (CAD) with age, the impact of this disease in the very old warrants further investigation. Objective To assess health outcomes and the attainment of guideline-based secondary prevention targets in the very old (>80 years, n = 482) as compared to young (<65 years, n = 582) and elderly (between 65 and 80 years, n = 932) patients, all of whom had chronic stable angina. Design The coronary artery disease in general practice (CADENCE) study was a cluster-stratified cross-sectional survey. This study reports on health outcomes quantitated using the Seattle Angina Questionnaire and guideline targets achieved for blood pressure, smoking, lipids, diabetic control and body habitus. Settings and participants 2031 stable angina patients were recruited from 207 primary care practices. Results Despite similar angina frequency scores, the very old were more physically impaired by their angina than both the young and elderly [76 ± 25 (Young) vs. 70 ± 26 (Elderly) vs. 63 ± 28 (Very old), p < 0.05 for both comparisons]. However, the very old had better quality of life scores than young stable angina patients [72 ± 24 vs. 65 ± 25, p < 0.05] and were similar to the elderly [72 ± 24 vs. 72 ± 23, p > 0.05]. Also blood pressure, lipid, diabetic and body habitus targets were more often achieved in the very old and elderly patients compared to young stable angina patients. Conclusion Despite similar symptomatic status and greater physical limitations, the very old reported a better quality of life and more often achieved treatment targets than young stable angina patients. Failure to improve secondary prevention measures in younger age groups may potentially contribute to increased morbidity in older age, and failure to achieve ‘Healthy Ageing’.</description><subject>80 and over</subject><subject>Age Factors</subject><subject>Aged</subject><subject>Angina</subject><subject>Angina, Stable - epidemiology</subject><subject>Angina, Stable - physiopathology</subject><subject>Angina, Stable - prevention & control</subject><subject>Australia - epidemiology</subject><subject>Blood Pressure</subject><subject>Cardiovascular</subject><subject>Chronic Disease</subject><subject>Coronary Artery Disease - epidemiology</subject><subject>Cross-Sectional Studies</subject><subject>Diabetes Mellitus - blood</subject><subject>Diabetes Mellitus - epidemiology</subject><subject>General Practice</subject><subject>Glycated Hemoglobin A - metabolism</subject><subject>Humans</subject><subject>Hypercholesterolemia - blood</subject><subject>Hypercholesterolemia - epidemiology</subject><subject>Hypertension - epidemiology</subject><subject>Hypertension - physiopathology</subject><subject>Middle Aged</subject><subject>Obesity - epidemiology</subject><subject>Practice Guidelines as Topic</subject><subject>Quality of Life</subject><subject>Secondary Prevention</subject><subject>Smoking - epidemiology</subject><subject>Stable</subject><subject>Surveys and Questionnaires</subject><issn>1443-9506</issn><issn>1444-2892</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9ks9u1DAQxiMEoqXwAFyQj0Uiwf82m1AJKaQBKlVtpS1InCzHmex6ydrBdor23Xg4HLblwAHJkufw-77RzDdJ8pLgjGCSv91mm0FlFBOa4TLDmD1KjgnnPKVFSR__qVlaLnB-lDzzfosxWXJWPk2OKCNsWRJynPy6MOhGBg0mePRThw2qN84ardAqyHYAVJm1NvINWoGyppNuj24c3EVcW4OqcQTpPPoAIYBD2qCwAfQVInU9dKi2u1E66FCw6JudzDoyD83eoduI1jY2m00rF2bVufYgPcxO6-YKnBzQ6KQKum7QaV2dN1d18xqtptaHqds_T570cvDw4v4_Sb58bG7rz-nl9aeLurpMFcdFSHlXMOhVuWS8LRVWfY4XC7pQhGFZKM4pBxKrnqmyBdrngPOeFS2THSkIZT07SU4PvqOzPybwQey0VzAM0oCdvCA5iQ9jTiNKDqhy1nsHvRid3sUJBcFiDk1sRQxNzKEJXIoYWtS8uref2h10fxUPKUXg7ABAHPJOgxNexSUq6LQDFURn9X_t3_-jVoOOCcvhO-zBb-3kTNyeIMJHjVjNVzMfDZlNimLJfgM-07zz</recordid><startdate>20130201</startdate><enddate>20130201</enddate><creator>Rajendran, Sharmalar, FRACP, PhD</creator><creator>Visvanathan, Renuka, FRACP, PhD</creator><creator>Tavella, Rosanna, BSc(Hons), PhD</creator><creator>Weekes, Andrew J., BMBS</creator><creator>Morgan, Claire, BSc Physio</creator><creator>Beltrame, John F., FRACP, PhD</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20130201</creationdate><title>In Patients with Chronic Stable Angina, Secondary Prevention Appears Better in the Very Old Compared to Younger Patients: The Coronary Artery Disease in gENeral practiCE (CADENCE) Substudy</title><author>Rajendran, Sharmalar, FRACP, PhD ; Visvanathan, Renuka, FRACP, PhD ; Tavella, Rosanna, BSc(Hons), PhD ; Weekes, Andrew J., BMBS ; Morgan, Claire, BSc Physio ; Beltrame, John F., FRACP, PhD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c408t-4d83efc9734b9c0cf605525c130a8c4424e10a8f3c9be2f6e06f38b3ad18123f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>80 and over</topic><topic>Age Factors</topic><topic>Aged</topic><topic>Angina</topic><topic>Angina, Stable - epidemiology</topic><topic>Angina, Stable - physiopathology</topic><topic>Angina, Stable - prevention & control</topic><topic>Australia - epidemiology</topic><topic>Blood Pressure</topic><topic>Cardiovascular</topic><topic>Chronic Disease</topic><topic>Coronary Artery Disease - epidemiology</topic><topic>Cross-Sectional Studies</topic><topic>Diabetes Mellitus - blood</topic><topic>Diabetes Mellitus - epidemiology</topic><topic>General Practice</topic><topic>Glycated Hemoglobin A - metabolism</topic><topic>Humans</topic><topic>Hypercholesterolemia - blood</topic><topic>Hypercholesterolemia - epidemiology</topic><topic>Hypertension - epidemiology</topic><topic>Hypertension - physiopathology</topic><topic>Middle Aged</topic><topic>Obesity - epidemiology</topic><topic>Practice Guidelines as Topic</topic><topic>Quality of Life</topic><topic>Secondary Prevention</topic><topic>Smoking - epidemiology</topic><topic>Stable</topic><topic>Surveys and Questionnaires</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rajendran, Sharmalar, FRACP, PhD</creatorcontrib><creatorcontrib>Visvanathan, Renuka, FRACP, PhD</creatorcontrib><creatorcontrib>Tavella, Rosanna, BSc(Hons), PhD</creatorcontrib><creatorcontrib>Weekes, Andrew J., BMBS</creatorcontrib><creatorcontrib>Morgan, Claire, BSc Physio</creatorcontrib><creatorcontrib>Beltrame, John F., FRACP, PhD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Heart, lung & circulation</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rajendran, Sharmalar, FRACP, PhD</au><au>Visvanathan, Renuka, FRACP, PhD</au><au>Tavella, Rosanna, BSc(Hons), PhD</au><au>Weekes, Andrew J., BMBS</au><au>Morgan, Claire, BSc Physio</au><au>Beltrame, John F., FRACP, PhD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>In Patients with Chronic Stable Angina, Secondary Prevention Appears Better in the Very Old Compared to Younger Patients: The Coronary Artery Disease in gENeral practiCE (CADENCE) Substudy</atitle><jtitle>Heart, lung & circulation</jtitle><addtitle>Heart Lung Circ</addtitle><date>2013-02-01</date><risdate>2013</risdate><volume>22</volume><issue>2</issue><spage>116</spage><epage>121</epage><pages>116-121</pages><issn>1443-9506</issn><eissn>1444-2892</eissn><abstract>Background With our aging communities and the increased prevalence of coronary heart disease (CAD) with age, the impact of this disease in the very old warrants further investigation. Objective To assess health outcomes and the attainment of guideline-based secondary prevention targets in the very old (>80 years, n = 482) as compared to young (<65 years, n = 582) and elderly (between 65 and 80 years, n = 932) patients, all of whom had chronic stable angina. Design The coronary artery disease in general practice (CADENCE) study was a cluster-stratified cross-sectional survey. This study reports on health outcomes quantitated using the Seattle Angina Questionnaire and guideline targets achieved for blood pressure, smoking, lipids, diabetic control and body habitus. Settings and participants 2031 stable angina patients were recruited from 207 primary care practices. Results Despite similar angina frequency scores, the very old were more physically impaired by their angina than both the young and elderly [76 ± 25 (Young) vs. 70 ± 26 (Elderly) vs. 63 ± 28 (Very old), p < 0.05 for both comparisons]. However, the very old had better quality of life scores than young stable angina patients [72 ± 24 vs. 65 ± 25, p < 0.05] and were similar to the elderly [72 ± 24 vs. 72 ± 23, p > 0.05]. Also blood pressure, lipid, diabetic and body habitus targets were more often achieved in the very old and elderly patients compared to young stable angina patients. Conclusion Despite similar symptomatic status and greater physical limitations, the very old reported a better quality of life and more often achieved treatment targets than young stable angina patients. Failure to improve secondary prevention measures in younger age groups may potentially contribute to increased morbidity in older age, and failure to achieve ‘Healthy Ageing’.</abstract><cop>Australia</cop><pub>Elsevier B.V</pub><pmid>23137911</pmid><doi>10.1016/j.hlc.2012.09.003</doi><tpages>6</tpages></addata></record> |
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| subjects | 80 and over Age Factors Aged Angina Angina, Stable - epidemiology Angina, Stable - physiopathology Angina, Stable - prevention & control Australia - epidemiology Blood Pressure Cardiovascular Chronic Disease Coronary Artery Disease - epidemiology Cross-Sectional Studies Diabetes Mellitus - blood Diabetes Mellitus - epidemiology General Practice Glycated Hemoglobin A - metabolism Humans Hypercholesterolemia - blood Hypercholesterolemia - epidemiology Hypertension - epidemiology Hypertension - physiopathology Middle Aged Obesity - epidemiology Practice Guidelines as Topic Quality of Life Secondary Prevention Smoking - epidemiology Stable Surveys and Questionnaires |
| title | In Patients with Chronic Stable Angina, Secondary Prevention Appears Better in the Very Old Compared to Younger Patients: The Coronary Artery Disease in gENeral practiCE (CADENCE) Substudy |
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