Identification of putative pathogenic microRNA and its downstream targets in anaplastic lymphoma kinase–negative anaplastic large cell lymphoma

Summary Anaplastic large cell lymphomas (ALCL) are tumors of T/null-cell lineage characterized by uniform CD30 expression. The 2008 World Health Organization classification subdivided ALCLs into 2 groups: anaplastic lymphoma kinase (ALK)–positive (established entity) and ALK-negative (proposed new e...

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Veröffentlicht in:	Human pathology 2014-10, Vol.45 (10), p.1995-2005
Hauptverfasser:	Mehrotra, Meenakshi, PhD, Medeiros, L. Jeffrey, MD, Luthra, Rajyalakshmi, PhD, Sargent, Rachel L., MD, Yao, Hui, PhD, Barkoh, Bedia A., MS, Singh, Rajesh, PhD, Patel, Keyur P., MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Anaplastic large cell lymphoma Classification Experiments Expression profiling Female Gene expression Gene Expression Regulation, Neoplastic - genetics Humans Hybridization In Situ Hybridization Kinases Lymphoma Lymphoma, Large-Cell, Anaplastic - enzymology Lymphoma, Large-Cell, Anaplastic - genetics Male Methods microRNA MicroRNAs MicroRNAs - genetics Middle Aged Morphology Oligonucleotide Array Sequence Analysis Pathogenesis Pathology Polymerase chain reaction Proteins Real-Time Polymerase Chain Reaction Receptor Protein-Tyrosine Kinases - biosynthesis Reverse Transcriptase Polymerase Chain Reaction Rodents RT-PCR Studies Young Adult
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