Inhibitory Actions of Synthesised Polyamine Spider Toxins and Their Analogues on Neuronal Voltage-Activated Calcium Currents

The whole cell variant of the patch-clamp technique was used to investigate the actions of polyamine spider toxins and their analogues on high voltage-activated Ca 2+ currents. The actions of synthesised FTX (putative natural toxin from the American funnel web spider), sFTX-3.3, Orn-FTX-3.3 and Lys-...

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Veröffentlicht in:	Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology Comparative pharmacology and toxicology, 1997, Vol.116 (1), p.23-32
Hauptverfasser:	Sutton, Kathy G, Stapleton, Simon R, Timms, Graham, Gilmore, Jeremy, Brust, Paul F, Bleakman, David, Scott, Roderick H
Format:	Artikel
Sprache:	eng
Schlagworte:	Cultured neurones high voltage-activated calcium channels polyamines spider toxins synthesised FTX ω-Agatoxin IVA
Online-Zugang:	Volltext
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