Mechanical unfolding of a simple model protein goes beyond the reach of one-dimensional descriptions

We study the mechanical unfolding of a simple model protein. The Langevin dynamics results are analyzed using Markov-model methods which allow to describe completely the configurational space of the system. Using transition-path theory we also provide a quantitative description of the unfolding path...

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Veröffentlicht in:	The Journal of chemical physics 2014-10, Vol.141 (13), p.135102-135102
Hauptverfasser:	Tapia-Rojo, R, Arregui, S, Mazo, J J, Falo, F
Format:	Artikel
Sprache:	eng
Schlagworte:	Markov Chains Models, Molecular Pictures Protein Unfolding Proteins Proteins - chemistry Thermodynamics
Online-Zugang:	Volltext
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